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MOBILion Systems and Protein Metrics join forces to integrate the Byos Software Suite with high-resolution ion mobility mass spectrometry

MOBILion Systems
27 Jan 2021
Edward Carter
Publishing / Media

Industry news

Protein Metrics and MOBILion Systems have announced their strategic partnership to provide data analysis modules for Protein Metrics’ Byos software suite that work exclusively with MOBILion’s High-Resolution Ion Mobility (HRIM) Mass Spectrometry (MS) System. This combination of data analysis and high-resolution analysis of multiple Critical Quality Attributes (CQA) is designed to accelerate biotherapeutic drug development and enhance characterization capabilities that affect product quality, safety, and efficacy.

MOBILion’s HRIM product addresses deficiencies in current biopharmaceutical characterization workflows that rely on Liquid Chromatography Mass Spectrometry (LCMS). This best-in-class separations technology enables rapid and reproducible molecular and structural characterization of biotherapeutics with two-minute, highresolution released glycan analysis and five-minute peptide mapping while providing more complete monitoring of Post Translational Modifications (PTMs).

Protein Metrics' Byos Platform enables researchers to move from raw data files to report in just minutes, with the click of a mouse. Designed to manage the burgeoning volume and complexity of analytical data, the platform has established itself as an analytical workhorse for protein characterization in biopharmaceutical laboratories.

The union of both platforms delivers on the promise of eliminating impediments to identifying and characterizing CQAs with the reliability, repeatability and speed required in modern biopharmaceutical organizations developing more complex protein therapeutics.

“Combining the fastest, highest resolution, most reproducible therapeutic protein analysis with simple, automated data analysis and visualization provides our mutual pharmaceutical customers with a streamlined workflow that will help bring safer, more efficacious drugs to market faster”, said Melissa Sherman, CEO of MOBILion Systems. “The push button, software driven approach of both the sample analysis and data analysis deliver the speed and efficiency our customers seek.”

“The whole is clearly greater than the sum of parts” remarked Kevin Cronin, Vice President Corporate Development at Protein Metrics. “With over 100 companies worldwide trusting our protein analysis workflows and an industry-recognized gold standard in glycan analysis, this partnership enables our client base to rapidly integrate cutting edge platforms with confidence and ease."

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.BiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.Ion Mobility SpectrometryData AcquisitionData acquisition refers to the collection and organization of information and data sets.

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