SelectScience
Join Free
Accelerating Science
NewsSeparations

Millipore Now Offers ProSep<sup>®</sup> Ultra Plus Prepacked Columns

Merck
12 Nov 2008

Product news

Millipore Corporation, a Life Science leader providing technologies, tools and services for bioscience research and biopharmaceutical manufacturing, today announced the availability of ProSep Ultra Plus Prepacked Columns.

ProSep Ultra Plus chromatography media, launched earlier this year, is now available in a convenient, easy-to-use prepacked column format. ProSep Ultra Plus Prepacked Columns are ready to use, small scale columns that are an ideal tool for initial media screening, scaling and optimization studies. The prepacked columns are available in 1 mL, 2.5 mL and 5 mL sizes and are compatible with any lab scale chromatography system.

ProSep Ultra Plus media is the highest capacity protein A chromatography media, delivering up to 50% greater productivity for today's higher titer therapeutic antibody processes. It is an affinity resin with the highest dynamic binding capacity (>50mg/ml at 10% breakthrough with 3-6min residence time) and flow rate capability of any comparable resin on the market. Based on the proven technology of ProSep chromatography media, ProSep Ultra Plus media can deliver the most cost effective solution to protein A affinity MAb capture processing. In addition, its rigid base matrix enables predictable scale-up and greater process flexibility, presenting users with the opportunity to reduce the equipment footprint.

Links

MerckCompany website

Tags

Flash ChromatographyFlash chromatography is a fast-preparative column chromatography technique used for separation and purification of liquid analytes. Flash chromatography systems use small silica gel particles for separation and a pressurized gas for driving the solvent through the column or pre-packed cartridge. Find the best flash chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Thin Layer ChromatographyThin-layer chromatography (TLC), also called planar chromatography, is an inexpensive and simple liquid chromatographic technique used to separate and identify small amounts of compound in a mixture, monitor progress of a reaction or determine purity of substance. TLC plates come in multiple sizes with common adsorbent layers being silica, aluminum oxide or cellulose and high-performance (HP-TLC) plates are also available for increased sensitivity. Other equipment needed includes TLC developing chambers, applicators, TLC sprayers and visualizing devices, such as a viewing cabinet and UV lamp. Find the best TLC products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

Related articles

Millipore Now Offers ProSep<sup>®</sup> Ultra Plus Prepacked Columns