Millipore licenses Neurofilament ELISA from Encor Biotechnology and the University of Florida

26 Mar 2007
Kerry Parker
CEO

Product news

Millipore Corporation today announced collaboration with Dr. Gerry Shaw from the University of Florida and EnCor Biotechnology, Inc to develop and license an enzyme-linked immunosorbent assay (ELISA) kit. This kit accurately measures the levels of pNF-H, a sensitive biomarker of axonal injury, in homogenates of tissues as well as samples of serum, CSF and other bodily fluids.

The neurofilament ELISA kit can be used in research not only for detecting the extent of spinal cord and brain injuries, but also finding axonal degeneration in neurological diseases, such as ALS and multiple sclerosis. The kit measures upregulation of pNF-H in a variety of damage, intoxication and disease states. This assay functions on all mammalian species tested to date, including rat, mouse, rabbit, cat, pig, cow and human.

“Partnering with a pioneer like Dr. Gerry Shaw, who founded EnCor and has prospered in an amazing biotechnology incubator at the University of Florida, is a privilege for Millipore,” said Kumar Bala, Marketing Director for Antibody Technology Bat Millipore. “We believe collaborations like this will accelerate discovery and therapy in the field of degenerative diseases, and Millipore is committed to further partnering with scientists at leading academic, biotech and government institutions to supply research tools worldwide which will accelerate breakthroughs in medicine and therapies,”

Dr. Gerry Shaw, professor in the Department of Neuroscience at the McKnight Brain Institute at the University of Florida College of Medicine, founded EnCor Biotechnology in December 1999. EnCor manufactures markets and researches high quality antibodies and proteins. In December 2004, EnCor, Dr. Shaw and a collaborator, Dr. Brian Pike at the National Institutes of Health, announced a patent pending on the ELISA assay.

Millipore’s Bioscience Division provides innovative tools, services and biological reagents that drive advancements in biomedical and academic research as well as support the discovery and development of new pharmaceuticals. The product portfolio has been further enhanced with the 2006 addition of Chemicon, Upstate and Linco product lines, allowing Millipore to provide the most complete offering of life science tools on the market. Our customers work in leading research laboratories across a variety of industries throughout the world. Millipore improves their laboratory productivity and efficiency through optimized workflows. For more information, please contact Millipore Tech Service at 1-800-548-7853 or 951-676-8080 or visit the article webpage.

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ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :
Millipore licenses Neurofilament ELISA from Encor Biotechnology and the University of Florida