Millipore Introduces Industry's First Flow Cytometry Kits for Chemokine Receptors

12 Nov 2008
Samantha Rosoman
Campaign Coordinator

Product news

Millipore has announced the availability of 11 new flow cytometry kits for chemokine receptorquantification. The FlowCellect™ Chemokine Receptor Surface Expression Quantification Kits are the first flow cytometry kits of their kind. They provide rapid, sensitive assessments in various cell types.

Such assessments create a new standard in cell biology research, according to Jason Whalley, senior product manager for cell biology. “Rapid assessments of chemokine receptor expression can be used in many applications, including research on infectious disease and inflammation,” he explained. “As a plus, the level of expression can be quantified by comparing signals from positive and negative cells, which are included in the assay kits. This way, researchers can avoid the hazard and expense of performing radioligand binding assays.”

Chemokines play critical roles in a number of cellular processes. They are involved in leukocyte trafficking and activation, mediated by 7-TM chemokine receptors. In addition, they are also widely expressed on immune system cells, and can serve as vital indicators of autoimmune disorders and HIV infections.

These FlowCellect kits and six others for stem cell research introduced on October 15, are optimized on Guava® EasyCyte™ flow cytometry systems as part of Millipore’s long-term partnership with Guava Technologies.

In March of this year, Millipore and Hayward, Calif.-based Guava Technologies, Inc. announced a long-term partnership to deliver integrated flow cytometry solutions to scientists conducting research in cell biology. These new stem cell kits are the first developed by Millipore’s research team in Temecula, Calif.

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Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :
Millipore Introduces Industry's First Flow Cytometry Kits for Chemokine Receptors