Millipore Announces Neurite Outgrowth Assay

7 Aug 2007

Product news

Millipore Corporation today announced the availability of its Neurite Outgrowth Assay, the newest assay kit in Millipore’s extensive drug discovery product line. Using high content screening for imaging and analysis of neurite outgrowth and neuronal cell morphology, the kit offers a complete solution for specificity labeling and neuronal cell bodies for High Content Imaging.

The kit utilizes high-quality, validated, target-specific detection reagents for profiling in a variety of species, including human, mouse and rat. Large scale screening is simplified through the assay reagents 24-hour stability at room temperature.

Its primary antibody is immunofluorescence-based to specifically label neurites and neuronal cell bodies in heterogeneous cell populations. High sensitivity-generating images with high signal-to-background ratios facilitate subsequent High Content Analysis, making the kit ideal for screening both inducers and inhibitors of neurite outgrowth neurotoxins.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Millipore Announces Neurite Outgrowth Assay