Microplates with non-binding surfaces

Greiner Bio-One announced at Medica 2007 novel microplates with an exceptionally high protein-repellent surface. The microplates developed at the company optimise biochemical active substance screening in that the influence of the plate surface on the test result is minimised.

The advanced non-binding surface highlights its usefulness in many areas where elevated binding of molecules, to the plate surface, such as peptides, DNA, RNA and proteins is specifically undesired. This is especially true for sensitive fluorescence or luminescence assays where high background or signal fluctuations can undermine assay performance and results i.e SPA (surface proximity assay).
The "non-binding" characteristic is not achieved through materials additives, rather through a chemical resin modification. This has the advantage that even longer incubation steps do not lead to leaching of the material.

The initial plates to receive the non-binding treatment are black, solid bottom 96 and 384 well microplates. However, additional plate types are available upon request.

Greiner Bio-One GmbH has been successfully involved in microplate manufacturing for many years and is used worldwide in laboratories for academic, biotech and pharmaceuti-cal research. With one of the largest selections of microplates in the world, Greiner Bio-One is one of the leading suppliers of plastic laboratory consumables for pharmaceutical active substance screening.