Microplate Help from Asynt

16 May 2007

Product news

Asynt, the specialist suppliers of solutions for organic synthesis, now distribute the Porvair Sciences range of microplates and microplate accessories for life science applications including drug discovery, combinatorial chemistry, SPE, protein purification, high throughput screening, proteomics and genomics.

Selecting the best microplate for a particular application can involve time consuming searches through the catalogues of different suppliers. Asynt’s technical team can offer advice and support and turn the extensive Porvair catalogue into a one-stop solution for virtually any application.

A feature of the range is the novel solutions developed to deal with specific microplate application problems. For example, it is common practice to use black plates to eliminate “cross talk” in fluorescence studies, and white plates to enhance sensitivity in luminescence assays. With normal white plates, very strong luminescence can cause false positive results, so the Porvair range includes black plates with white wells that eliminate the cross-talk problem without losing sensitivity.

Extensive evaluation and testing ensures that the materials used to manufacture Porvair microplates exhibit minimal leaching of chemicals into the sample, preventing contamination during storage and interference with analytical results. As a further precaution, ultrasonic welding is used to produce chemically inert, bleed-free joints.

Asynt also offer the Porvair range of ancillary microplate equipment, including evaporators, vacuum manifolds and sealing systems, and a range of reagent reservoir trays to fit most laboratory robots.

"Asynt’s breadth and depth of expertise in supplying tailored solutions to the analytical and preparative problems faced by chemists and biologists made them an ideal choice to become an authorised Porvair distributor" said Porvair Sales Manager, Steve Knight.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Microplate Help from Asynt