Mettler Toledo Provides a Pharmaceutical Weighing Guide to Improve Efficiency

13 Oct 2016
Lois Manton-O'Byrne, PhD
Executive Editor

Industry news

Mettler Toledo have produced a free second-edition pharmaceutical weighing guide which focuses on five typical lab workflows. The guide provides useful tips to improve balance operation, optimize material handling and enhance productivity while maintaining regulatory compliance in today’s busy pharmaceutical R&D, quality-control, or production lab.

In the highly competitive pharmaceutical industry, there is intense focus on laboratory efficiency. However, there are also stringent regulations to adhere to. Second edition of the weighing guide, “Efficient Workflows in the Pharmaceutical Industry”, is designed to help laboratories maintain regulatory compliance and optimize lab performance.

The guide discusses how careful lab-procedure analysis, elimination of inefficiencies, and - as much as possible - standardization of processes are keys to achieving both optimum performance and excellent accuracy. These actions remain constant regardless of the oversight system a lab adheres to, including Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP).

The updated and expanded edition of the guide includes five workflows:

  • Capsule filling
  • Culture media preparation
  • Titration sample preparation
  • Reference standards and solutions preparation, and
  • Quantitative elemental analysis sample preparation

Challenges inherent to each workflow such as repetitive actions, tight tolerances, user ergonomics and process hygienics are discussed in detail. Solutions such as process changes, special accessories and automation are then reviewed, allowing the reader to determine the level of handling required in their lab. Data integrity, connectivity and workflow guidance are also discussed.

Download the Efficient Workflows in the Pharmaceutical Industry Guide here.

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Balances and Moisture AnalyzersBalances & Moisture Analyzers / weighing scales measure static or dynamic loads. Features to consider when choosing an analytical balance include accuracy, capacity and resolution. Additional features and specialized balances include enclosures for weighing powder, microbalances for measuring small quantities, portable balances, moisture analyzers, top loading balances and internal calibration for measurements over time or with varied temperature.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.Elemental AnalysisElemental analysis involves determining the elemental composition of a sample, often used in environmental, pharmaceutical, and material sciences. Techniques like ICP-MS, X-ray fluorescence, and atomic absorption spectroscopy allow precise quantification of elements such as metals and nonmetals in complex matrices. Browse our peer-reviewed product directory to find the best elemental analysis tools, compare products, check reviews, and get pricing directly from manufacturers.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Cell CultureCell culture involves growing cells under controlled conditions, typically outside of their natural environment, to study cellular behavior, drug response, and disease models. Cell culture is crucial in biotechnology and biomedical research. Explore cell culture products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.