Merz Pharmaceuticals Outsources Compound Management to BioAscent

6 Mar 2017
Mia Harley
Biochemist

Industry news

BioAscent and Merz Pharmaceuticals GmbH, part of the Merz Pharma Group, have entered into a Master Service Agreement (MSA), under which BioAscent provides a comprehensive outsourced compound management service for a significant part of Merz Pharmaceutical’s compound collection, in both solid and liquid forms.

The compound management MSA is part of Merz Pharmaceutical’s outsourcing strategy to improve operational efficiency and cost-effectiveness. Under the agreement, which has been in operation since August 2016, BioAscent is responsible for the storage, plating, distribution, logistics and tracking of Merz Pharmaceutical’s compounds, supplying screen-ready plates as and when they are required. BioAscent’s Newhouse facility offers pharma and biotech companies scalable and highly secure infrastructure, with the flexibility to manage solid and liquid compounds in a wide range of tubes and microplates, between ambient and -20 °C. As well as having the infrastructure and specialist skills, BioAscent uses Titian Software’s industry-leading Mosaic sample management software for efficient transfer of data.

“Having reviewed the tender submissions, it was clear that BioAscent’s capabilities and management team were ideal for our requirements”, said Dr. Ulrich Abel, Principal Scientific Expert Pharmaceutical Chemistry at Merz. “Having made the decision to outsource our compound management to BioAscent, we have been very happy with the service; we have complete control and our requests are managed accurately and promptly. We were also really pleased with the ease of the hand-over process, which was less than one week, during which there was no overall disruption to our screening workflow.”

Dr Sylviane Boucharens, BioAscent’s COO/CSO commented: “Our facilities offer significant advantages for small to medium size organisations which may not have the day-to-day screening requirements to justify the investment in compound management equipment and facilities. Our modern facility - a former Pharma research site - has everything in place so that we can cost-effectively manage compound collections for screening workflows on an outsourced basis.”

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Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  Compound ScreeningCompound screening is a method used to discover specific compounds that could be promising candidates for pharmaceutical use. This potential is identified when compounds interact with the target protein during screening and could therefore be carried forward in the drug development process.Sample ProcessingSample processing is required to prepare samples prior to analysis. Technologies used for sample processing include homogenizers, grinders, mills and mixers.Sample HandlingProper and careful handling of samples is important in scientific studies to ensure the integrity of specimens. This will prevent deterioration and cross contamination, and improve the accuracy of sample tracking procedures.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.
Merz Pharmaceuticals Outsources Compound Management to BioAscent