MEDICA 2016: GATC Biotech Showcases World’s Only Service Lines for Direct Comparison of Liquid and Tissue Biopsy Samples

14 Nov 2016
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

GATC Biotech, a world-wide leading provider of innovative sequencing and diagnostic solutions, is pleased to present the company’s exclusive product portfolio for simultaneous analysis of tumor tissue and liquid biopsy samples at this year’s MEDICA. With GATCLIQUID, the world’s leading service line for liquid biopsy analysis, GATC Biotech offers the sole opportunity for exome, cancer panel or single gene sequencing from cell-free DNA (cfDNA). The same services are perfectly complemented by INVIEW sequencing solutions for genomic analysis of tumor tissue. Together or alone, the products offer mutation profiling of individual cancers for improved personalized monitoring of disease progression.

“The great thing about our cancer research portfolio is that we offer scientists the opportunity to compare liquid biopsy samples with matched tissue biopsies,” said Dr. Paprotka, Director Research & Development at GATC Biotech. “This compatibility makes comparative analysis of mutations detected in either liquid or tissue biopsies easily possible.”

The three highly-sensitive assays differ in the scope of mutational analysis. GATCLIQUID ONCOEXOME provides an overview of all somatic mutations in the protein coding regions of the tumor. INVIEW HUMANEXOME is this product’s complement for tissue biopsy analysis. GATCLIQUID ONCOPANEL and INVIEW ONCOPANEL target more than 200 actionable mutations from 50 carefully selected cancer drivers in blood or tumor tissue respectively. GATCLIQUID ONCOTARGET provides highly sensitive detection of a single tumor mutation that is the most informative in a specific cancer case.

“Data from concordance studies comparing liquid biopsies with standard tissue testing is urgently needed to help establish liquid biopsies in a clinical setting,” continued Dr. Paprotka. “Taking this into account, our expansive cancer research portfolio makes GATC Biotech the perfect partner for all clinical studies in the field of oncology diagnostics.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.MutationMutations are changes in the DNA sequence that can lead to diseases, including cancer and genetic disorders. Analyzing mutations is crucial in diagnostics, drug development, and personalized medicine. Explore mutation detection tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.Liquid BiopsiesLiquid biopsies are non-invasive tests used to detect cancer and other diseases by analyzing blood or other bodily fluids. This technique is gaining popularity for early detection, monitoring treatment response, and detecting minimal residual disease. Explore liquid biopsy solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.
MEDICA 2016: GATC Biotech Showcases World’s Only Service Lines for Direct Comparison of Liquid and Tissue Biopsy Samples