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MDS Analytical Technologies Introduces New Systems for Genomics Research

Molecular Devices®
24 Jun 2008

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MDS Analytical Technologies, a leader in innovative solutions for drug discovery and life sciences research, announced the release of three new molecular biology instruments designed to advance genomics and microgenomics discoveries for life sciences researchers. These instruments provide scientists flexible and open platforms to perform sensitive and specific molecular analysis in a number of fields, including stem cell research, cancer research, proteomics, drug discovery and many others.

Two new microarray scanners, the Axon GenePix® 4300A and the Axon GenePix® 4400A, represent the latest in a long line of industry-leading microarray detection and analysis systems from MDS Analytical Technologies. These newest platforms improve the efficiency of research experiments, reducing the cost per data point, and offer the broadest applicability in the microarray industry.

For researchers using laser capture microdissection (LCM), a method for isolating cells under a microscope, the new, next-generation ArcturusXT™ instrument uses the latest advances in microscope technology by employing the Nikon Eclipse Ti-E inverted research microscope as its base. This new technology improves speed, precision and flexibility during the microdissection process – shortening the length of time required for experiments and expanding application potential through an increased range of available options.

“These new products continue our tradition of innovation and excellence, offering reliability, flexibility, and high performance solutions for life sciences researchers,” commented Dr. Andy Boorn, president of MDS Analytical Technologies. “The Axon GenePix 4300A and 4400A scanners provide customers with the most advanced microarray applications in the industry, and keep us at the forefront of innovation in this growing field. The conversion of our ArcturusXT system to the Nikon Ti-E microscope provides our LCM customers with advanced research capabilities and flexibility.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.

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MDS Analytical Technologies Introduces New Systems for Genomics Research