Mass Based Purification: Introducing the New Gilson LCMS Purification System

26 Apr 2011
bridget bridget
Laboratory Director

Product news

Gilson Inc., an industry leader in purification systems for HPLC, SPE and GPC clean-up, introduces the latest in mass spec technology to the industry leading purification platforms. Gilson’s LCMS purification system combines industry leading mass spectrometry capabilities with mass ranges from 50 to 3000 amu and scan speeds up to 10,000 amu/sec with the most reliable liquid handling, injection and fraction collection platforms on the market today.

Gilson has taken the Trilution LC platform, a software package specifically designed for preparative purification, and added the FLEXAR Single Quad MS as a detector to trigger mass based fraction collection. Conditional logic collection of Trilution LC allows for utilizing UV, DAD, and up to seven target masses with up to 3 adducts per target mass in SIM or SCAN with Extracted Ion modes.

The system has been designed with the user in mind. Mass based purification no longer has to be an intimidating and difficult to use system. Control of the single quad is as simple and easy to follow as any detector in the software but provides the specificity and efficiency of mass based purification.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.