Market Leaders in Automated pKa, logP/D and Solubility Measurement

29 Aug 2011

Product news

Sirius Analytical design and manufacture highly automated instruments to measure physicochemical parameters - pKa, logP & logD, solubility and dissolution. The SiriusT3 is the next generation physchem measurement system which meets the needs of the pharmaceutical industry from early discovery all the way through to late stage formulation and development. Find out more about this instrument at the booth at Drug Discovery in Manchester in September.

The company also operate as a CRO providing a wide range of physical chemistry analytical services. The Analytical Service provides a reliable and cost-effective source for outsourcing PhysChem measurements. The service is available all year round to any clients, worldwide.

Services include:

Screening
- pKa
- LogD
- Surface Activity
Gold Standard
- pKa
- LogP
- Solubility
- GI Dissolution
- Solid State
Early Development
- Custom designed assays
- Understanding supersaturation
- Insights into BCS
- Evaluating the effects of excipients on solubility, supersaturation and dissolution

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.
Market Leaders in Automated pKa, logP/D and Solubility Measurement