Malvern Shows Two New Systems at 2012 AAPS Annual Meeting & Exposition

9 Oct 2012

Product news

Malvern Instruments’ new Zetasizer Nano ZSP and Morphologi G3-ID systems, both launched in the past month, will be on show on Booth #3230 at the 2012 American Society of Pharmaceutical Scientists (AAPS) Annual Meeting & Exposition in Chicago from 14th to 18th October 2012 as part of Malvern’s portfolio of analytical solutions for pharmaceutical and biopharmaceutical applications.

Launched in September, the Zetasizer Nano ZSP brings unique protein measurement and novel microrheology capabilities to the established and market-leading Zetasizer range of dynamic light scattering (DLS) systems. The Zetasizer Nano ZSP is a single, compact unit that shares the simplicity and ease of use that have made Zetasizer Nano systems a firm favourite in industry and academia for almost a decade. It adds unique performance specifications for both size and zeta potential measurement, one of the most significant applications being for the measurement of the zeta potential, or electrophoretic mobility, of proteins.

On 2nd October 2012, following the completion of a highly successful early access program, Malvern launched the Morphologi G3-ID particle characterization system to the global market. The Morphologi G3-ID combines automated particle imaging with the chemical identification of individual particles using Raman spectroscopy. It is a fully automated system that measures particle size, shape and chemical identity in a single platform and is ideally suited to solving complex particle characterization problems where particle size and shape do not provide sufficient information. Key applications for which it is proving especially valuable are in determining component-specific particle properties of mixtures and blends, such as the particle size of drug ingredients in nasal sprays and asthma inhalers, and in the identification of unknown or suspicious particles in injectable or parenteral products, for example.

Malvern specialists will be available throughout the event to discuss individual products and applications so visit Booth #3230 to find out more!

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Raman SpectroscopyRaman spectroscopy is used to discern the vibrational and rotational states of molecules and hence the chemical composition of a sample by measuring the inelastic scattering of monochromatic light. Explore a range of Raman spectrometers, including handheld/portable Raman spectrometers for QC/QA labs and in situ spectrometers for processes. Conduct Raman imaging for microanalysis of mixed samples using a Raman microscope. Raman spectrographs are also available. Find the best Raman spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.NanotechnologyNanotechnology, or nanotech, is an engineering technique using molecular scale functional systems. Applications of nanotechnology include medicine and medical devices, electronics, air and water purification, food science and energy production.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.RheologyProtein Measurement