Malvern Instruments Showcases the Morphologi G3-ID and Its OINDP Applications at DDL24

26 Nov 2013
Sarah Thomas
Associate Editor

Product news

Malvern Instruments is showcasing the innovative Morphologi G3-ID particle characterization system at Drug Delivery to the Lungs 24 (DDL24), from 11 - 13 December 2013 at the Edinburgh International Centre, Edinburgh, Scotland. During the event Malvern specialists will be on hand to demonstrate the Morphologi G3-ID and to illustrate the system’s increasing application within inhaled product development.

The Morphologi G3-ID forms part of Malvern’s expanding toolkit of technologies that are enabling researchers to understand and optimize the delivery of drugs using inhaler, nebulizer and nasal spray devices. By combining automated image analysis with Raman spectroscopy, the system provides the component-specific particle characterization capabilities required to study how particle size and shape, along with formulation composition, may affect drug delivery. When used alongside the real-time droplet and particle size data generated by the Malvern Spraytec laser diffraction particle size analyzer, this helps support more efficient and cost-effective development of both innovator and generic OINDP products.

Downloads from the Malvern website of particular interest for anyone working in this field include ‘Component specific particle characterization of dry powder inhalable drug products’ and ‘Laser diffraction and automated imaging – complementary techniques for nasal spray development’. These and other detailed resources are available via the Morphologi G3-ID page on the Malvern website which can be accessed by clicking the company website link below.

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Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Raman SpectroscopyRaman spectroscopy is used to discern the vibrational and rotational states of molecules and hence the chemical composition of a sample by measuring the inelastic scattering of monochromatic light. Explore a range of Raman spectrometers, including handheld/portable Raman spectrometers for QC/QA labs and in situ spectrometers for processes. Conduct Raman imaging for microanalysis of mixed samples using a Raman microscope. Raman spectrographs are also available. Find the best Raman spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drug DosageDosage is the size or frequency of the administration of a drug. Determination of the dosage of a drug is critical in pharmaceutical development to ensure the optimum balance between efficacy and toxicity.
Malvern Instruments Showcases the Morphologi G3-ID and Its OINDP Applications at DDL24