Malvern Instruments Experts Contribute Presentation, Run DLS Short Course and Exhibit at PEGS 2013

Contributing to the Analytical and Purification Streams at the protein engineering summit PEGS 2013, Dr Kevin Mattison, Principal Scientist, Bioanalytics, at Malvern Instruments will present a paper on ‘Avoiding Aggregation and Viscosity Challenges – Early Development Formulation Screening’. He will also be one of the instructors on Malvern’s Dinner Short Course, ‘How to Obtain Reliable Information from Light Scattering: Theory, Practical Advice and Data Interpretation’. Dr Mattison’s co-instructor will be Dr Ulf Nobbmann, Product Manager GPC/SEC Technologies.

PEGS 2013 takes place at the Seaport World Trade Center in Boston from April 29th to May 3rd. Dr Mattison’s presentation is on May 2nd and Malvern’s Dinner Short Course is on April 30th. The short course will examine: which key indicators assure reliable DLS and SEC-LS data quality; what are hydrodynamic size and polydispersity; how is the mass distribution determined by DLS and how valid is it; and, is light scattering suitable for quality control applications?

As in previous years, Malvern is a corporate sponsor and will be exhibiting from the range of solutions that it is driving ahead for characterizing proteins and their aggregates. On show for the first time at the Boston event will be the new Zetasizer Nano ZSP. Launched in September 2012, this top-of-the-range addition to Malvern’s established Zetasizer Nano family uses the technique of electrophoretic light scattering to enable the highly sensitive measurement of zeta potential for rapid, reliable determination of the electrophoretic mobility of proteins, and subsequent calculation of the key parameter of protein charge. Measuring protein mobility (or zeta potential) using this approach is faster and more convenient than conventional methods such as capillary electrophoresis and iso-electric focusing. Furthermore, the Zetasizer Nano ZSP requires only 20 microliters of sample and measures at concentrations down to 1 mg/mL.