Malvern Instruments’ 2014 Webinar Program Gets Underway with Light Scattering for Biopharma

24 Jan 2014
Sarah Thomas
Associate Editor

Product news

Malvern Instruments has kicked off another year of its highly popular open-access webinar program and on 21 January the ‘Step into the Light’ webinar offers insight into the use of dynamic light scattering technology to improve the quality of biopharmaceutical data in purity profiles. This is followed on 23 January by ‘Optimization and characterization of nanomaterials for drug delivery applications. Part 1 – Liposomes’ ‘Where do I find source material in light scattering?’ is the topic on 28 January, and the first of this year’s laser diffraction masterclass series goes out live on 30 January. For more information and to register for Malvern Instruments' webinars please visit click on the company website link below.

Accurately identifying impurities and generating purity profiles presents substantial challenges to biopharmaceutical developers, who require the most sensitive analysis methods available. ‘Step into the Light’ will explore the analytical challenges within biopharmaceutical development, including resolving trace impurities from active pharmaceutical ingredient (API) monomers and predicting aggregation propensity. The presentation will go on to investigate how and why dynamic light scattering systems, such as Malvern’s Zetasizer range, offer the sensitivity required for biopharmaceutical applications.

Amongst Malvern’s range of analytical solutions for biopharmaceutical applications are the market-leading Zetasizer systems which combine dynamic light scattering with electrophoresis capabilities to calculate the defining molecular features of proteins such as size and molecular weight as well as electrophoretic mobility. Zetasizer systems provide the advanced and accurate data needed to tackle development and manufacturing issues, including stability and aggregation.

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Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.
Malvern Instruments’ 2014 Webinar Program Gets Underway with Light Scattering for Biopharma