Major Pharma Chooses CompacT SelecT Automated Cell Culture Systemto Generate Consistent, High Quality Cell Plates for Transport Assays

1 Sept 2014
Kerry Parker
CEO

Product news

TAP Biosystems (now part of the Sartorius Stedim Biotech Group), a leading supplier of cell culture and fermentation systems for life science applications, is pleased to announce that its CompacT SelecT™, automated cell culture system has been chosen by a top ten pharmaceutical company to reliably produce consistent, high quality cells in plates, ready for use in transport assays.

CompacT SelecT is being routinely used to automatically culture and maintain a large range of cells in 24 and 96 transwell transport assay plates. With the system, researchers are setting up their cell culture seeding, feeding, expansion, plating and maintenance protocols to automatically produce consistent quality cells for extended periods of time. This flexible approach is allowing these scientists to have a constant supply of cell lines such as Caco-2 and MDCK for use directly in transport assays without having to perform time-consuming, error-prone manual media changes and feeding regimes at night or over weekends.

CompacT SelecT includes a unique SelFeeder liquid handling unit that allows scheduled feeds and media changes and also has a gentle liquid addition and removal action. This reduces damage to cell layers ensuring cell lines are successfully cultured for more consistent transport assay results.

Dr Dave Thomas, Product Manager at TAP Biosystems commented: "We’re delighted that this progressive pharma company is using our automated cell culture technology so successfully. Their adoption of the system to reproducibly generate high quality cell lines indicates to scientists looking to improve their workflow, as well as their transport assay performance that CompacT SelecT is a tried and trusted choice.”

CompacT SelecT™ SC Automated stem cell culture system

TAP Biosystems

CompacT SelecT SC cultures multiple stem cell lines in parallel in T-Flasks and plates without cross contamination. Offers reliable and consistent maintenance, expansion and differentiation of stem cell lines. CompacT SelecT™ is the leading automated cell culture system, used in labs across commercial and academic life science. It is now available with new options to enable the culturing of complex cell lines for oncology programmes, stem cell research and toxicity studies.CompacT SelecT SC provides a solution for core stem cell facilities and academic labs conducting basic stem cell research programs. Can also be used as a platform for the provision of stem cells for drug discovery screening programs and cell therapy research programs.CompacT SelecT grows cells from multiple cell lines in T-flasks for cell line maintenance and expansion. It can generate assay-ready plates on demand for cell-based screening and assay development.CompacT SelecT™ SC Automated stem cell culture system Automates: Expansion and maintenance of multiple cell lines Sub culturing Expanding cell numbers through the seeding of a number of flasks Transient transfection Harvesting and plating of cells for assays and screening Harvesting of cells in flasks for off-line processing Incubation of up to 90 T 175 format flasks and 210 plates Cell counting and viability measurement Processing of single, Triple and 10 layer (HYPERFlask) flasks Plating into 96 and 384-well plates

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell GrowthCell growth refers to the process by which cells increase in size and number. It is essential for tissue development, wound healing, and cancer research. Understanding and controlling cell growth is a fundamental part of cell biology and regenerative medicine. Browse our peer-reviewed product directory to find the best tools for studying cell growth, compare products, check reviews, and get pricing directly from manufacturers.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.