Lumigen HyPerBlu from Beckman Coulter Provides Sensitive Chemiluminescent Detection of Hydrogen Peroxide

31 Mar 2010
Sarah Sarah
Marketing / Sales

Product news

Lumigen HyPerBlu enables direct detection of hydrogen peroxide. Combining a broad dynamic range and bright, sustained chemiluminescence, the ready-to-use reagent offers unmatched convenience for high-throughput screening laboratories.

Reaction of the substrate with hydrogen peroxide rapidly generates sustained high-intensity luminescence for maximum sensitivity in solution assays. Direct detection increases accuracy and simplifies data analysis. When coupled with oxidases, the reagent also allows reliable, one-step, indirect detection of oxidases or their substrates.

HyPerBlu is provided as a single solution and does not require mixing. It is stable for one year when stored in an amber bottle at 2-8 degrees C.

“Detection of hydrogen peroxide is an important and widely used component of the drug discovery process,” noted Ed Pagani, vice president and general manager of molecular diagnostics, Beckman Coulter, Inc. “HyPerBlu saves time and delivers accurate results, qualities that should be highly desirable to researchers in high-throughput screening laboratories.”

Links

Tags

High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Lumigen HyPerBlu from Beckman Coulter Provides Sensitive Chemiluminescent Detection of Hydrogen Peroxide