Lokon Pharma and Affibody initiate a collaboration to develop novel cancer therapeutics

The partnership aims to combine oncolytic viruses with Affibody® molecules

12 Jan 2022
Peter Manfre
Publishing / Media

Industry news

Lokon Pharma AB, a leading biotech company in the area of immunostimulatory gene therapy for cancer delivered by uniquely engineered oncolytic viruses, today announced a collaboration with Affibody AB (“Affibody”) to combine oncolytic viruses with Affibody® molecules.

“Lokon’s oncolytic adenovirus platform encodes human immunostimulatory genes to induce anti-tumor immunity in cancer patients. We already have one virus in clinical development, LOAd703, and we are expanding our pipeline to meet the demand of different types of malignancies” says Dr. Angelica Loskog, the CEO of Lokon Pharma. She adds, “Affibody’s proprietary antibody mimetics are small proteins with high affinity to desired targets and well suited to combine with our LOAd platform viruses. We are excited to initiate this new collaboration aiming to develop a novel treatment regime for selected cancer indications”.

“We are enthusiastic about investigating this potential extension of our Affibody® technology platform by collaborating with leading researchers in the oncolytic virus field”, says Prof. Fredrik Frejd, CSO of Affibody. “The small size of and potential for high affinity makes Affibody® molecules highly interesting tools for a novel treatment regime with adenovirus platforms”.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.
Lokon Pharma and Affibody initiate a collaboration to develop novel cancer therapeutics