Linkam showcases cryo capabilities at M&M 2023

Linkam unveils the CMS196 and CryoGenium Systems

23 Jul 2023
James Li
Blood Banking Scientist

Industry news

Linkam Scientific Instruments will be showcasing a range of temperature-controlled stages at the Microscopy and Microanalysis conference 2023 (M&M) on July 23–27. With a focus on its cryo-correlative portfolio, Linkam will present its cryo-correlative systems – the CMS196 and the CryoGenium plunger, host live tutorials on system operation and performance, and display a poster at the event.

The CMS196 is a cryo-correlative stage which can be used for the correlation of biochemical processes within cells. Providing high-resolution structural information from electron microscopy (EM) images, it can be interfaced with a variety of upright microscopes and is an integral part of a correlative light and electron microscopy (CLEM) workflow. The system also supports reduced sample contamination, improved sample handling, and enhanced stability for super-resolution cryo imaging.

The CryoGenium is one of the company’s newest developments in electron microscopy (EM) grid vitrification. The system aims to address problems faced by users using Cryo-EM, cryo-tomography, single particle tomography (SPT) and cryo-CLEM, as the novel design replaces the common blotting mechanism to improve process stability and repeatability. This is done through the system’s patented suction method, with optical monitoring to adjust the sample thickness in a controllable manner.

Linkam will be at booth #1420 in the Minneapolis Convention Center, and the CryoGenium tutorials will be taking place on the booth on July 24, 25 and 26 at 17:45 CDT.

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Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Electron MicroscopyElectron microscopes (EM) are used to create high-resolution images of samples at the nanoscale by means of an accelerated beam of electrons as a source of illumination. Types of electron microscope include scanning electron microscopes (SEM), transmission electron microscopes (TEM), scanning transmission electron microscopes (STEM) and cryo-electron microscopes. Focused ion beam (FIB) microscopes are useful for modifying or milling a sample surface with nanometer precision, as well as imaging. Find the best electron microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MicroscopyMicroscopy is a technique used to observe small objects in detail, from cells to materials, using light or electron microscopes. It enables researchers to examine structures with high resolution, aiding in fields such as biology, medicine, and materials science. With advanced microscopy techniques, scientists can gain insights into cellular processes, tissue structures, and material properties. Explore the best microscopy solutions in our peer-reviewed product directory, compare products, read customer reviews, and get pricing directly from manufacturers.Cryogenic
Linkam showcases cryo capabilities at M&M 2023