Linkam launches new stage of CMS196 cryo-stage to combine cryo-CLEM

The latest updates to the CMS196V⁴ stage includes an improved user interface featuring a touch-panel and joystick, alongside an encoded and motorised XY stage which allows high-precision automated mapping of sample grids. The new stage also features different sample holders and interface options for the newly-interchangeable optical bridge for imaging.

Cryo-CLEM microscopy integrates the benefits of fluorescence and electron microscopy, and the CMS196V⁴ supports full cryo-CLEM workflows. Sample safety remains a key feature of the CMS196V⁴ stage, with researchers able to handle and transfer cryo samples without risk of contamination. Improved cable management and simplified topology improve ease of installation and use. Additional new features include a cordless magnetic heated lid, auto-fill dewar with drip-feed, and an objective lens heater for superior drift performance.

Linkam has also developed a Modular Imaging Platform, which offers significant improvements to sample access. It features a motorised Z-axis control and sliding mechanism to make it easier to access samples, and a modular design to support multiple microscopy techniques.

“The modifications to our market-leading cryo-stage provide researchers with a valuable tool to unlock new insights using Cryo-CLEM microscopy. The new features will allow researchers to exert more control over their stage configuration, while also enjoying simplified set-up with improved topology and overall user experience,” says Clara Ko, Sales and Marketing Director, Linkam Scientific Instruments.

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