LGC Standards launches new 13C-labelled PFAS reference materials to support EPA Method 1633 workflows

LGC Standards has announced the expansion of its Dr. Ehrenstorfer™ PFAS portfolio with new 13C-labelled reference materials specifically developed for EPA Method 1633, including two ready-to-use isotope labelled internal standard (EIS/NIS) mixtures (24 and 7 analytes) and a comprehensive range of single compound solutions.

These materials are designed to streamline calibration, improve data quality, and deliver robust, defensible results across aqueous, solid, and biological matrices, enabling laboratories around the world to produce reliable, traceable PFAS measurements.

The new labelled mixtures include:

• EPA Method 1633 EIS Labelled PFAS Mixture (24 analytes; 0.25–5 µg/mL, 1 mL; Part No. DRE-A50000792MW) - Added before extraction to track sample preparation recovery.
• EPA Method 1633 NIS Labelled PFAS Mixture (7 analytes; 0.25–1 µg/mL, 1 mL; Part No. DRE-A50000794MW) - Non-extracted Internal Standard Added before injection to correct for instrument response.

Both mixtures are engineered for stability and routine use, helping laboratories reduce calibration runs, compensate for matrix effects and instrument variability, and avoid the need to develop inhouse blends. They match the method’s prescribed values, supporting reliable quantitation and compliance.

“With EPA Method 1633 now the recommended multi-matrix standard for PFAS analysis, laboratories need stable, traceable isotope labelled materials they can trust,” said Dr Kelly Cheshire, Global Segment Manager, LGC Standards. “Our new 13C-labelled mixtures and singles — simplify workflows, enhance quantitation, and help labs save time.”

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