Launch of TruSight Oncology 500 DNA/RNA application accelerates oncology research

Beckman Coulter Life Sciences, in partnership with Illumina, offers a promising new approach to oncology research delivering faster results with fewer touchpoints. The Illumina TruSight™ Oncology 500 DNA/RNA assay on the Biomek NGeniuS System from Beckman Coulter Life Sciences provides an innovative automated solution enabling comprehensive genomic profiling of tumor samples.

The application supports both DNA and RNA inputs, enabling the detection of critical cancer biomarkers including single nucleotide variants (SNVs), insertions, deletions, gene amplifications, fusions, and splice events. Complete library preparation can be achieved in less than three days, providing faster results with automated precision from sample preparation to sequencing.

Four to 24 libraries can be processed in a single batch, accommodating both high-quality and low-quality FFPE samples. The assay is also optimized for reduced plastic use and lower consumable costs, making cutting-edge research more accessible and sustainable.

The new application joins the Illumina DNA Prep, DNA PCR-Free Prep, and RNA Prep with Enrichment applications, which are all available in a first-of-its-kind open chemistry, cloud-based Biomek NGeniuS System Applications Library.

The Biomek NGeniuS System is a purpose-built liquid handler for low-medium throughput next generation sequencing (NGS) library preparation. It provides an easy-to-use automation solution that reduces user-errors, manual transfers, and hands-on time for the traditionally labor-intensive process of NGS library construction.

The Illumina TruSight Oncology 500 DNA/RNA sample preparation method and additional applications centered around cancer research, infectious disease research, and targeted sequencing is the latest installment in a series of automation application collaborations between the two companies.

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