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Latest Compass™ 1.2 Software with Support for Leading Liquid Chromatography Systems and API-Sources

Bruker Daltonics
17 Sept 2007

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Bruker Daltonics announced the release of Compass™ 1.2 software for its HCT™ high-capacity ion traps and micrOTOF™ ESI-(Q-q)-TOF mass spectrometers, providing significant new functionality for customers. The new Compass version 1.2 offers a variety of new features and workflows for proteomics and small molecule applications, including Electron Transfer Dissociation (ETD) with the HCTultra high-capacity ion trap PTM discovery system™.

A partner program allows efficient and application oriented development of HPLC software plug-ins in close collaboration with our HPLC partner companies. Currently, the following major LC product lines are supported: Agilent 1100/1200/1200 RR HPLC systems, Waters Alliance and ACQUITY UPLC systems, Dionex Ultimate3000, Hitachi LaChromElite and Eksigent Express, plus the CTC PAL auto sampler.

Compass 1.2 is fully compatible with CompassOpenAccess™ LC/MS walk-up operation and with CompassSecurityPack™ for working in regulated environments. It also fully supports all important atmospheric pressure ionization sources for proteomics and small molecule applications like ESI, APCI, simultaneous ESI/APCI (multimode), APPI, nano-electrospray sources, or a CE-MS interface.

Compass is Bruker Daltonics’ unified software environment for all life science mass spectrometers with an intuitive and easy-to-use graphical user interface (GUI). It provides straight-forward instrument control and data processing for all Bruker Daltonics LC/MS, FTMS and MALDI-TOF mass spectrometers.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.MALDI-TOF MSMALDI-TOF mass spectrometers (matrix-assisted laser desorption/ionization time-of-flight) are used for the mass analysis of large molecules, including proteins, DNA, polymers and other macromolecules due to its relatively soft ionization, reducing fragmentation whilst allowing fast data acquisition. Tandem mass analyzers such as TOF/TOF systems can be used to increase resolution and sensitivity of your analysis. Find the best MALDI-TOF products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Latest Compass™ 1.2 Software with Support for Leading Liquid Chromatography Systems and API-Sources