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Latest Clinical Downloads Available from the SelectScience® Library

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A selection of the latest clinically relevant application notes, infographics and case studies

13 Jun 2016
Sonia Nicholas
Managing Editor and Clinical Lead

Editorial article

The SelectScience® downloads library is constantly updated with new content.

This article highlights some of the most recent articles available to download. Learn more about the latest cryostorage tubes, advances in cancer screening technology, novel cryo-fluorescence microscopy and the latest infectious disease diagnostics.

1. Benchmark Performance of Thermo Scientific Matrix 2D-Barcoded Cryostorage Tubes

The study in this application note tests the performance of Thermo Scientific™ Matrix™ 2D-barcoded cryostorage tubes against other popular brands to assess their suitability for this task. Since the primary role of these tubes is to maintain samples without allowing any alterations during their time in storage, it is critical to ensure that any tube chosen is robust enough to perform under harsh storage conditions.

2. Slide Loader Enhances Cancer Screening Services

This application note provides an overview of how the PL200 slide loader from Prior Scientific can aid pathologists in diagnosing cancer. The PL200 allows the user to load, scan, and unload multiple loads automatically, greatly increasing the efficiency of the process.

3. Cryo-Confocal Imaging with Airyscan Improving Resolution and Signal-to-Noise in Cryo-Fluorescence Microscopy

This application note describes how the ZEISS Airyscan can improve resolution and Signal-to-Noise in cryo-fluorescence microscopy, it allows the user to record high-quality cryo- fluorescence data even without immersion optics, thanks to its novel confocal detection scheme.

4. Detection of Ten Common STI Pathogens

More than 1 million people acquire a sexually transmitted infection (STI) every day, creating need for early diagnosis and treatment to prevent more complications in the future. This poster from Randox describes a multiplex array on a biochip platform to detect ten common STI pathogens simultaneously from one sample. This method increases detection capacity and saves time compared to methods where each pathogen must be detected individually.

5. Serological Tests for The Diagnosis of Zika, Dengue and Chikungunya Virus Infections

Zika virus belongs to the arboviruses of the Flaviviridae family. The virus is generally not transmitted between humans. In individual cases, however, transmission via sexual intercourse has been reported. This application note provides an overview of the process of serological differential diagnosis in suspected cases of dengue, chikungunya or Zika virus infections (DENV, CHIKV, ZIKV).

6. Infographic: Lab Automation Selection Process

Automating your lab is a detailed process. This infographic provides a high-level view of the steps to select a laboratory automation solution.

7. Prospective Application of the Luminex xTAG® GPP Multiplex PCR in Diagnosing Infectious Gastroenteritis

Identification of enteric pathogens currently incorporates a range of different methods with varying sensitivities, specificities, and turn-around times. In this application note, the clinical performance of the xTAG® Gastrointestinal Pathogen Panel (xTAG® GPP), a new qualitative bead-based multiplexed molecular diagnostic test, is established.

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HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Fluorescence MicroscopyFluorescence microscopy has become an essential tool in biology, as well as in materials science. The application of many fluorochromes has made it possible to identify cells and sub-microscopic cellular components with a high degree of specificity. Using multiple fluorescence labels, different probes can simultaneously identify several target molecules.Infectious DiseasesInfectious diseases are caused by pathogens such as bacteria, viruses, and fungi. Effective detection, prevention, and treatment are crucial to control outbreaks and improve public health. Diagnostic tools, vaccines, and antimicrobial treatments are essential components of managing these diseases. Research into emerging pathogens and resistance patterns continues to evolve. Browse our peer-reviewed product directory to find the best diagnostic tools, prevention solutions, and treatment options; compare products, read customer reviews, and get pricing directly from manufacturers.

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