Large volume sample pooling made easy

30 May 2007

Product news

Genevac has announced a new innovation in solvent evaporation technology that enables scientists to pool and productively concentrate large volume sample fractions directly into a single standard sample vial.

For high-throughput applications including compound storage, drug development and environmental analysis, methods that can reduce analytical work are desirable. Pooling of fractions that contain a common analyte, to yield a single sample, save time and are therefore highly desirable. Until now though no commercial technology existed for pooling and concentrating large volume fractions.

Available in 3 sizes (50ml, 125 ml and 300ml) the ingenious patented design of SampleGenie™ enables Genevac's popular EZ-2 and HT series centrifugal evaporators to accelerate the pooling of multiple large volume fractions into a single small sample vial. Constructed in a choice of glass or 316L stainless steel a SampleGenie® is available to cope with most solvent types.

Using SampleGenie™ a HT-4X evaporator was able to dry 24 samples in parallel, each containing 50 ml of water in less than 9 hours. Used in conjunction with Genevac's LyoSpeed™ methods - 24 samples each containing 25ml of water / acetonitrile (60:40) were fast lyophilised in only 6 hours 45 minutes.

Many years of experience in solvent evaporation and sample purification have allowed Genevac to produce high-efficiency sample concentrators that deliver high performance, ease of use, high reliability, and compatibility with most commonly used solvents and acids. The new SampleGenie™ accessory further extends the utility of these systems to be able to provide a truly efficient tool for pooling and rapid concentration of large volume samples.

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CentrifugesCentrifuges are used to separate particulates suspended in a liquid via the application of a centrifugal force including cells, macromolecules, nanoparticles and precipitates. Centrifuges come in three sizes: microcentrifuges, benchtop and floor-standing centrifuges, depending on the volume and number of samples that require separation. When choosing a centrifuge, consider its maximum separation power indicated by its relative centrifugal force (RCF) value. Low force centrifuges reach a maximum RCF of 8,000 g, high-force centrifuges can reach maximum RCF values of 80,000 g. For extremely high forces, consider ultracentrifuges (up to 800,000 g). Refrigerated and vacuum centrifuges also known as concentrators are available for more specialized applications. A range of volumes are available for centrifuge tubes and microfuge tubes, depending on sample sizes. Find the best centrifuges in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.Evaporators and Freeze DryersCentrifugal evaporation is used for solvent removal from a sample. This is a useful technique for sample concentration or sample drying. Many centrifugal evaporators are modular with a central vacuum pump for generating low pressure. Useful features of evaporators or vacuum ovens include minimal solvent bumping, solvent resistance, computer control, temperature regulation and benchtop design.
Large volume sample pooling made easy