LAB7 SYSTEMS Launches BioBuilds, SeqSigma, and DashO3 to Accelerate and Streamline Genomic Data Processing

2 Sept 2013
Sarah Thomas
Associate Editor

Product news

Lab7 Systems, Inc., announced today that it has released a free software toolkit and new service offerings for the next-generation DNA sequencing (NGS) bioinformatics community, along with the latest beta version of its Lab7 Dashboard. BioBuilds™ is a reference collection of Open Source bioinformatics tools for genomics, pre-built for Linux and Mac OS X platforms. It eliminates the need for users to maintain and build their own versions of these tools. By providing binaries, BioBuilds also enables users to easily reproduce results by removing version dependencies on underlying software, since all tools in BioBuilds will be pre-built for those binaries.

“Open Source software is important for bioinformatics”, said Chris Mueller, Ph.D., Lab7 Systems’ President and Chief Technology Officer. ”However, building and maintaining Open Source tools can be a time consuming process. We maintain internal builds of many analytical tools and we feel that making our builds freely available is a good way to give back to the genomics community.”

“Everything we’re launching today supports our vision of a streamlined environment for the management and analysis of NGS data.” Chris Mueller, President & CTO.

BioBuilds is being released in conjunction with the second Public Beta of the Lab7 Dashboard, the company’s comprehensive software platform for managing sequencing projects, workflows, and pipelines. This release includes the Production Pipeline Engine, a complete sequence analysis pipeline management and report generation system. The Production Pipeline Engine allows users to easily port existing analysis pipelines into a managed, production-ready environment. All BioBuilds tools are made readily available in the Lab7 Dashboard, even though the platform is not expressly required to run the tools.

Lab7 Systems also launched its SeqSigma™ and DashO3™ optimization processes, integral components of the company’s larger suite of custom services. The SeqSigma process utilizes clients’ sequencing and analysis goals to design and implement cost-effective computational infrastructures that scale with their labs, while the DashO3 pipeline optimization process identifies computational and dataflow bottlenecks in sequence analysis pipelines and can increase performance by two- to tenfold.

“Everything we’re launching today supports our vision of a streamlined environment for the management and analysis of NGS data,” concluded Dr. Mueller. “With the tools we’re providing, we know that we can reduce the burden on bioinformaticians, scientists, and clinicians, allowing them to refocus their efforts to accelerate scientific discovery and clinical diagnoses.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
LAB7 SYSTEMS Launches BioBuilds, SeqSigma, and DashO3 to Accelerate and Streamline Genomic Data Processing