KeraFAST Introduces FASTCell™ Meta-Keratin--Breakthrough Cell Culture Coating Material

13 Dec 2010
Kerry Parker
CEO

Product news

KeraFAST today announced the introduction of FASTCell™Mera-Keratins, a line of products that make use of KeraFAST's proprietary human keratin biomaterials, which can be used in place of tissue culture coatings such as collagen or basement membrane extract (e.g., Matrigel™). Available as a lyophilized powder for reconstitution as a coating material, the Mera-Keratin product line is highly purified, sterile, and free of any animal materials. Meta-Keratins contain structural features such as binding domains that are recognized by integrin receptors to promote cell surface attachment.

KeraFAST takes advantage of proprietary isolation technologies exclusively licensed from the laboratory of Dr. Mark Van Dyke at the Wake Forest Institute for Regenerative Medicine to produce four preparations of human keratin: Meta-Keratin I, Meta-Keratin II, Meta-Keratin III and Meta-Keratin IV, each of which, like other cell culture coatings, differs subtly in its capacity to emulate the extracellular matrix (ECM) and promote growth, differentiation and function in various cell types.

Bob Bondaryk, Ph.D., Chief Operating Officer at KeraFAST said: “These Meta-Keratin products are the first in a family of Keratin xeno-free products that we will introduce in the near future. We have already received great reviews from our beta-site laboratories testing the products over the past several months. By helping cell lines to attach, proliferate and differentiate, we’re seeking to make life easier for researchers culturing hard-to-grow cells.”

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Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
KeraFAST Introduces FASTCell™ Meta-Keratin--Breakthrough Cell Culture Coating Material