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IONTAS Announces New Antibody Optimization Agreement with Teva Pharmaceuticals

IONTAS
30 Jul 2019
Georgina Wynne Hughes
Editorial Assistant

Industry news

IONTAS Limited, a leader in antibody discovery and optimization of human monoclonal antibody libraries, has announced an agreement with Teva Pharmaceuticals to apply its technologies and know-how to the optimization of human antibodies for use as biotherapeutics.

Under the terms of the agreement, IONTAS will initially apply its proprietary technologies to provide Teva with a panel of optimized antibodies against a defined target. Teva will have the option to enter into further optimization programs in the future. The agreement also includes options for the screening of biophysical properties suitable for developable antibodies.

Dr John McCafferty, Founder and Chief Executive Officer of IONTAS, commented: “Our experience in both antibody discovery and optimization enables us to generate antibodies that meet the stringent characteristics required by our Partners and the selection of IONTAS by Teva is a validation of this know-how and expertise. With our ability to focus on function, affinity, specificity and developability we can generate lead antibodies with lower risk of Chemistry, Manufacturing and Controls issues.”

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.CollaborationBiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.BiotechnologyBiotechnology is the use of biological processes, organisms, or systems in the production of products and services. It spans a wide range of applications, including healthcare, agriculture, and environmental management. Browse our peer-reviewed product directory to find the best biotechnology tools, compare products, check reviews, and get pricing directly from manufacturers.

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IONTAS Announces New Antibody Optimization Agreement with Teva Pharmaceuticals