InVitria Expands Animal-Free Cell Culture Tools Portfolio with OptiVERO

4 Apr 2018
Han Yin
Administrator / Office Personnel

Product news

InVitria, a division of Ventria Bioscience has launched OptiVERO, a chemically defined, blood- and plant hydrolysate-free cell culture media for vaccine manufacturing that outperforms popular VERO media by enabling robust VERO cell expansion and production of difficult-to-express virus types.

“Unlike other VERO media currently available, OptiVERO does not contain undefined di- and tri-peptide plant-derived hydrolysates. OptiVERO provides scientists with the unrivaled ability to minimize cell culture variability, thereby accelerating vaccine research and speeding manufacturing time for crucial vaccines,” said Randall Alfano, vice president of product development at InVitria.

Serum and di/tri-peptide plant-derived hydrolysates can cause variability in cell expansion, hindering viral replication and ultimately, reducing the productivity of the cell culture system. Therefore, media with undefined components can increase the time and resources required to manufacture a vaccine. OptiVERO replaces unrefined components with highly pure and biologically active recombinant human transferrin and albumin to formulate a chemically defined media optimized specifically for VERO-based virus production in both 2D and 3D cell cultures. This product builds on InVitria’s portfolio of blood-free components to improve performance, consistency, quality, and safety of cell culture media for the development of novel cell-based therapeutics.

“This technology sets the new standard for vaccine development — by removing all undefined components, InVitria is making it possible to culture previously difficult-to-express virus types and commercially produce new, life-saving vaccines that weren’t scalable before with serum-based or plant hydrolysate-containing media,” Alfano added.

At the World Vaccine Congress, InVitria will present growth performance and viral production data demonstrating the high performance of OptiVERO compared to serum-based media and chemically-defined industry standards.

Do you use cell culture media from InVitria? Write a review today for your chance to win $400 Amazon voucher.

Links

Tags

Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Labware and Lab SuppliesLabware and lab supplies include various forms of glassware, plasticware, reagents and personal protective equipment (PPE) and are used across all scientific laboratories, enabling daily tasks to be performed. Explore a range of flasks and beakers, petri dishes, carboys and storage bottles. Labware such as condensers, desiccators and burettes are also available for more specific tasks. Find the best labware and lab supplies in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Vaccine DevelopmentVaccine development focuses on creating immunizations to protect against infectious diseases. The process involves identifying antigens, developing and testing vaccine efficacy, and ensuring safety through preclinical testing and multiple clinical trial phases. Scientists use various approaches, including weakened or inactivated viruses, protein subunits, or mRNA. Advanced platforms and rapid diagnostic tools aid in vaccine research and testing. Explore vaccine development solutions in our peer-reviewed product directory; compare products, read reviews, and get pricing directly from manufacturers. Cell CultureCell culture involves growing cells under controlled conditions, typically outside of their natural environment, to study cellular behavior, drug response, and disease models. Cell culture is crucial in biotechnology and biomedical research. Explore cell culture products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.