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Invetech Co-Develops CellKey for MDS Sciex

Invetech
7 Aug 2006
Kerry Parker
CEO

Product news

Invetech, specialist in instrument development and custom automation which exhibits at Drug Discovery Technology & Development 2006 on booth #738, announces development of the unique CellKey™ technology. Successfully launched to market in September 2005, CellKey™, a high information secondary screening instrument employing Cellular Dielectric Spectroscopy (CDS), was completed within 21 months. Invetech was commissioned by MDS Sciex, to collaborate on development of the new CellKey™ technology.

The CellKey™ platform is a fully automated system for secondary screening laboratories and target validation. A unique technology for analysis, CellKey™ enables label-free and universal measurements of endogenous and transfected receptors, irrespective of their coupling mechanism. Kinetic measurements are taken in real-time with all wells of the microplate being read in parallel.

The collaboration allowed MDS Sciex to maximise its R&D by utilizing the capabilities of Invetech as its development partner.

Invetech, which exhibits at Discovery Technology & Development 2006, is participating in a seminar about this project at 9am, Wednesday 9 August. More information on the seminar is available at www.drugdisc.com. In addition, an indepth flyer on the collaboration is available free of charge on booth #738.

For more information about Invetech’s innovative instrument development techniques and custom automation services, please contact Invetech on Invetech@scottmail.co.uk, visit the website article webpage, phone East Coast US: +1 203 675 4502, West Coast US: +1 415 533 1958, or visit on booth #738 at Drug Discovery Technology and Development.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.

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Invetech Co-Develops CellKey for MDS Sciex