Intelligent Design Makes Automated Chemistry Affordable

17 May 2007

Product news

By looking at automated chemical synthesis from a completely different perspective, leading chemistry innovator, Syrris has cut the expected cost of a system by up to 60%. At just one third of the price of other automated reactors, Syrris’s atlas provides real price benefits, delivering full functionality to accommodate a broad range of applications, for just a fraction of the cost.

Known for its innovative technologies and expanding product lines, Syrris has developed atlas as a modular, cost-effective tool that allows a range of functions including heating, stirring, cooling and automated reagent addition to be carried out. Such modularity enables the system to be scaled up for greater throughput or experimental complexity when required. Intelligent design allows atlas to work as a simple or programmable reaction stirrer when used as a stand-alone unit or as a sophisticated controlled lab reactor when connected to a PC, and integration with existing third party laboratory instrumentation is easily achieved.

Key to its ongoing success is its affordability and ease-of-use. Front panel controls are intuitive for simple pre-programming of experimental parameters such as temperature, stirring and reagent addition profiles, and various experimental set-ups are accommodated. For example, a range of base inserts are available for round–bottomed flasks (50 ml to 1000ml), a unique clip-in overhead stirrer can be incorporated for use with more viscous solutions, and quick-click reactor clamps allow flasks and jacketed reaction vessels to be easily clicked into place without additional clamps or straps.

David Easson, Vice President of Manufacturing and Process Development at Epic Therapeutics (Norwood, MA), has incorporated atlas into his laboratory, "We recently purchased two atlas systems and have been delighted with their performance, ease-of-use and flexibility. In addition, the lower cost of the systems made our decision-making process very easy” says Easson, adding “The atlas software makes the equipment particularly simple to operate alongside a wide range of our existing laboratory instrumentation for efficient system control and data logging."

For more information on Syrris’s modular chemistry systems, atlas and FRX please visit the article webpage.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.
Intelligent Design Makes Automated Chemistry Affordable