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Integromics Launches OmicsHub Proteomics 2.0., a Data Management and Analysis Tool for Mass Spectrometry Laboratories

Integromics
12 Jun 2011
bridget bridget
Laboratory Director

Product news

Integromics today announces the availability of OmicsHub® Proteomics 2.0, a new version of the OmicsHub product adding several new features to its existing centralized data management and analysis capabilities for mass spectrometry laboratories and core facilities.

OmicsHub Proteomics 2.0 is a result of extensive research by Integromics into the needs of mass spectrometry laboratories and core facilities. Resulting from this research, Integromics inserted several new features and benefits specifically requested by central figures in the market, including: protein quantification, protein validation, a pathway viewer, automatic reports, an OMSSA search engine, background importation and user roles and permissions.

The web-based multi-user, centralized data management and analysis OmicsHub platform will allow users to address the poor reliability and human error issues and time and data management complexity associated to mass spectrometry experiments. It addresses the problems that most mass spectrometry laboratories and core facilities encounter on a daily basis by performing automatic tasks such as batch searches on multiple search engines (Mascot, Phenyx, OMSSA), label-free protein quantification, protein validation and functional annotation (UniProt, InterPro, GO, Panther, etc.), pathways integration or automated report generation, resulting in reduced errors, time and data management complexity.

OmicsHub Proteomics is the first product available on the market that allows mass spectrometry researchers to create experiments in a PRIDE XML format for tandem MS based experiments (MS/MS) as well as for peptide mass fingerprinting experiments (MS) or combine experiments (MS+MS/MS).

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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