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Integrated DNA Technologies (IDT) Launches its Fully Licensed Minor Groove Binder Eclipse® GMP Probes to its Online Service

Integrated DNA Technologies Inc.
24 Jun 2015
Chelsie Phillips
Temporary Editorial Assistant

Product news

Integrated DNA Technologies (IDT), has become the only company to add fully licensed Minor Groove Binder (MGB) Eclipse® GMP probes to its online service, enabling quick and efficient ordering. These robust and economical qPCR probes are the latest addition to the company’s product portfolio of GMP probes and primer GMP-produced and supplied under license for use as components in human in vitro diagnostic tests. Diagnostics test manufacturers can now benefit from a faster turnaround time for MGB Eclipse probes, receiving products with full GMP traceability.

Facilitating fast and accurate detection and measurement of abnormal or foreign DNA in cell samples, the demand for quantitative real-time PCR (qPCR) assays for in vitro diagnostics has rapidly grown, highlighting the need for easily available high-quality probes. The gold standard for 5′ nuclease qPCR assays is set by three critical features in oligonucleotide probes: fluorescent reporter dyes, quenchers for these dyes, and a minor groove binder. MGB Eclipse probes meet this standard, containing a choice of FAM, HEX™, or TET™ fluorescent markers, Eclipse™ Dark Quenchers, and the Minor Groove Binder (MGB™). Diagnostic test providers are supplied with an extensive and reliable choice of readily available, high-quality probes for their end-use applications thanks to Coupling MGB Eclipse probes with IDT’s expertise in oligonucleotide and GMP manufacturing.

The efficient service provided by IDT’s online ordering system for gene expression and genotyping GMP probes and primers, which include multiple fluorophore and quencher options, benefits hospitals, CLIA and reference labs, among others. Diagnostic test providers also benefit from the same turnaround time, and ISO 13485-certified production processes, providing the fully transparent and traceable product history afforded by IDT’s GMP business strategy. This ensures customers will receive products that meet elevated standards for all their diagnostic requirements.

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PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.In VitroIn vitro refers to experiments conducted outside living organisms, often in controlled lab environments such as petri dishes or test tubes. In vitro models are widely used in drug testing, cell biology, and disease research. Explore in vitro research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.qPCRQuantitative PCR (qPCR) is a molecular biology technique used to amplify and measure the amount of a specific DNA or RNA target. It plays a crucial role in gene expression analysis, pathogen detection, and quantifying DNA or RNA in various applications. Real-time PCR provides precise, quantitative results and is widely used in research, diagnostics, and clinical studies. Browse our peer-reviewed product directory to find the best qPCR solutions; compare products, check reviews, and get pricing directly from manufacturers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.In Vitro DiagnosticsIn vitro diagnostics (IVD) involve testing samples outside the body, typically in a laboratory, to diagnose diseases or conditions. IVD technologies include blood tests, molecular assays, and other bodily fluid tests, enabling accurate diagnosis and monitoring of diseases. These tests are essential for guiding treatment decisions in clinical settings. Browse our peer-reviewed product directory to find the best IVD solutions; compare products, check reviews, and get pricing directly from manufacturers.RT qPCRReal-time quantitative PCR (RT-qPCR) is a technique used to measure gene expression and quantify DNA or RNA in real-time. It is essential in genomics, diagnostics, and biotechnology research. Explore RT-qPCR systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Integrated DNA Technologies (IDT) Launches its Fully Licensed Minor Groove Binder Eclipse® GMP Probes to its Online Service