INTEGRA’s pipetting solutions support business diversification

Learn how BioApp Solutions enhances liquid handling efficiency with INTEGRA Biosciences' pipettes

2 Dec 2024

The VIAFLO 96 handheld electronic pipette streamlines repetitive, labor-intensive pipetting tasks.

The VIAFLO 96 handheld electronic pipette streamlines repetitive, labor-intensive pipetting tasks.

INTEGRA Biosciences’ pipettes are being used by BioApp Solutions to semi-automate and streamline its repetitive liquid handling protocols. The devices have enabled the company to improve pipetting consistency within its sample analysis and method development workflows, ensuring more reproducible results.

BioApp is a specialist provider of bioanalytical training and consultancy services. The company provides bespoke sample analysis, early-stage method development, workflow optimization and validation services in-house. The team was seeking a liquid handling instrument that would perform error-prone and time-consuming repetitive tasks, choosing INTEGRA’s VIAFLO 96 handheld electronic pipette with a 96 channel pipetting head and 300 μL automation GRIPTIPS® pipette tips.

BioApp also acquired a selection of five single and multichannel EVOLVE manual pipettes in volumes from 2-300 μL – paired with ECO rack GRIPTIPS – for smaller sample numbers and volumes, and for spiking samples with known concentrations of analytes in preliminary studies. Having several pipettes dedicated to different tasks helps to reduce the risk of cross-contamination and provides added flexibility, alleviating throughput limitations.

Mohammed Abrar, Director and Co-founder of BioApp, described the benefits for the lab, “We use the VIAFLO 96 for sample dilutions and mixing, extracting supernatants, and sample loading during supported liquid extraction protocols. Pipetting protocols for labor-intensive tasks can be intuitively and conveniently programmed into the pipette. This has greatly improved our productivity, giving us time to focus on more stimulating tasks and helping to safeguard our mental and physical health.”

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GripTips for VIAFLO 96/384

INTEGRA Biosciences

When working with a 96- or 384-channel system such as the VIAFLO 96/384, it is essential that the pipette tips are reliably attached. Due to the unique design, the GripTip system ensures that the tips will never accidently fall off, even when performing a tip touch on the sidewall of a vessel. Pipetting with multiple channels into a well plate is a precision task. GripTips for VIAFLO 96/384 undergo an additional quality check for tip straightness, guaranteeing accurate pipetting in 96- and 384-well plates. Depending on the tip size, GripTips are packaged in two different tip boxes. Larger volume GripTips (300 µl, 1250 µl) are delivered in boxes of 96 tips. The smaller volume GripTips (12.5 µl, 125 µl) are filled in a space efficient 384-fold grid in XYZ boxes. These boxes house 4 times as many tips and feature the standard SBS-footprint. All tips are available in non-sterile, sterile or filtered sterile configuration. Features and benefits: • GripTips snap onto the tip fitting of the pipetting head, which prevents tips from falling off. • An additional quality check ensures that pipette tips are perfectly straight, enabling precise pipetting in multi well plates. • Filtered GripTips reliably protect the pipetting head against contaminations caused by aerosols.

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EVOLVE Manual Pipettes

INTEGRA Biosciences

Set volumes fast! The EVOLVE manual pipette features three adjustable dials to rapidly set volumes. This revolutionary approach reduces repetitive stress injuries and allows users to set volumes in a fraction of the time it takes with a traditional manual pipette. GripTip pipette tips that will never fall off EVOLVE pipettes together with INTEGRA’s wide range of GripTips form a perfect pipetting system. GripTips snap into place with minimal tip loading effort, providing a secure connection. GripTips never fall off and are perfectly aligned, ensuring precise touch offs of fluids resulting in superior pipetting performance. Operational comfort Two differently sized plunger springs allow users to customize the force needed to depress the plunger to their preference. The controlled plunger spring option allows users to slow the aspiration and dispense speeds resulting in improved pipetting technique and results. The controlled plunger spring is compatible with all single channel EVOLVE pipettes except the 5 ml model. Changing the spring is completed in seconds. The ultra lightweight, well balanced design of the pipettes provides unsurpassed ergonomics even during prolonged pipetting sessions. EVOLVE pipettes are available as single, 8,12 and 16 channel models. Features: Quick Set Dials Unlike traditional pipettes which utilize a single rotating plunger to set volumes, EVOLVE features one dial for setting each of three volume digits. This is the same convenient method used to unlock three dial combination locks. This revolutionary approach allows users to set volumes more than ten times faster than standard manual pipettes. Simply depress and twist the plunger to unlock the quick set volume dials. Once unlocked, freely adjust the three dials to rapidly set the desired volume. Volumes set on traditional manual pipettes can often change while pipetting due to unintentional plunger turns. The EVOLVE Quick Set Dial design prevents inadvertent volume drift due to plunger movements while pipetting. GripTip System Do your pipette tips ever loosen, leak or fall off? This is a common issue in laboratories, caused by the use of universal pipette tips. Such tips require “hammering on” which stretches the shape of the pipette tip rim. The stretched pipette tip rim immediately starts moving back to its original shape, away from the tip cone. This can cause leaking, misaligned tips and even pipette tips that completely fall off the pipette! This will never happen with any EVOLVE pipette / GripTip combination. Featuring a low attachment force and a low ejection force, GripTips effortlessly snap onto the tip fittings and are easily ejected. Also, GripTips feature a high lateral resistance once attached to the EVOLVE pipettes. This means GripTips are always firmly attached and perfectly aligned, regardless of how many side well touch offs are performed. You no longer have to hammer your pipette tips on or worry about pipette tips falling off! Interchangeable Plunger Spring Assemblies Two differently sized plunger springs allow users to customize the force needed to depress the plunger to their preference. The controlled plunger spring option allows users to slow the aspiration and dispense speeds resulting in improved pipetting technique and results. The controlled plunger spring is compatible with all single channel EVOLVE pipettes except the 5 ml model. Changing the spring is completed in seconds. INTEGRA Linear Stand Storing pipettes upright is important to prevent liquid or debris from entering the tip fitting. Proper storage also extends the life of a pipette. The INTEGRA linear stand is ideal for hanging EVOLVE pipettes up off the lab bench. Up to twelve manual pipettes can be placed on a linear stand. EVOLVE shelf hooks are also available for proper storage.

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CRO ServicesExplore the comprehensive range of services offered by Contract Research Organizations (CROs) to streamline drug development and clinical research. From preclinical studies to regulatory support and clinical trials, CROs provide expert solutions that help pharmaceutical and biotech companies bring products to market faster and more efficiently.Pipettes and DispensersPipettes and dispensers are essential lab equipment used to dispense measured volumes of liquid accurately. Explore a range of manual and electronic pipettes, including single and multichannel, serological and volumetric pipettes, as well as a range of pipette tips. Bottle-top dispensers are also available for simple and fast solvent dispensing. Find the best pipettes & dispensers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Liquid HandlingLiquid handling involves the precise transfer, mixing, and dispensing of liquids in laboratory settings. It is essential for accurate and consistent results in biological, chemical, and pharmaceutical research. Automated liquid handling systems improve efficiency and reduce human error in sample preparation and analysis. Explore liquid handling tools in our peer-reviewed product directory; compare products, read customer reviews, and get pricing directly from manufacturers.PipettesPipette TipsPipette tips are essential accessories used in laboratory settings for transferring precise volumes of liquids. They come in various sizes and materials to accommodate different types of samples, ensuring accuracy and contamination prevention. Browse our peer-reviewed product directory to find the best pipette tips for your laboratory needs, compare products, check reviews, and get pricing directly from manufacturers.Electronic PipetteElectronic pipettes are precision instruments used to transfer measured volumes of liquid in laboratory settings. They offer high accuracy, ease of use, and ergonomic benefits compared to traditional pipettes, reducing the risk of repetitive strain injuries. Electronic pipettes are widely used in molecular biology, chemistry, and diagnostics. Browse our peer-reviewed product directory to find the best electronic pipettes; compare products, check reviews, and get pricing directly from manufacturers.Method DevelopmentMethod development is the process of creating and optimizing experimental techniques and protocols to achieve reliable, reproducible results. This is essential in various fields, including pharmaceuticals, environmental science, and diagnostics. Browse our peer-reviewed product directory to find the best method development solutions, compare products, check reviews, and get pricing directly from manufacturers.Bioanalysis