Institut Pasteur Korea selects ActivityBase™ as its Screening Solution of choice

20 Sept 2006

Product news

IDBS today announced that Institut Pasteur - Korea has implemented the ActivityBase data management software suite to increase efficiency and throughput in its screening operations. Institut Pasteur Korea (IP-K), a new Research Center located in Seoul, South Korea, has purchased ActivityBase to handle their biology and chemistry data for High Throughput and High Content Screening (HTS/HCS).

IP-K is implementing HCS assays and platforms for Drug Discovery using cell-based models of disease and automated confocal microscopy. IP-K will use ActivityBase suite to consolidate chemistry information and screening results, including those from microscopy-based screens, in a single Oracle database. Institut Pasteur Korea decided to purchase ActivityBase as its researchers felt more secure with a system with a proven track record in Drug Discovery.

Dr. Thierry Christophe, the Head of the Screening and Pharmacology lab, has used ActivityBase in previous positions at other companies. He said “I am happy to be working with ActivityBase again, as it is a robust and flexible system that I know can deliver the results we need. We plan to develop specific data analysis templates for High Content Screens allowing the manipulation of multiplexing data from one single screen.”

Neil Kipling, IDBS’ Chairman and CEO, commented: “The increase in HCS and HTS planned by IP-K’s screening group demanded a data management system that could scale up to their requirements, both now and in the future, as well as map closely to their workflow. We are delighted to be supporting a centre of excellence in biomedical research and technology development, allowing new drugs to be identified faster and more reliably.”

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Integration ServicesIncorporate lab systems, software and equipment with integration services.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.