InSphero and Hamilton have announced collaboration to improve the production and handling of spheroids using advanced liquid handling technology

24 May 2021
Ellen Simms
Product and Reviews Editor

Industry news

InSphero AG, a pioneer of 3D cell-based assay technology, and Hamilton, an innovation-driven leading supplier of automated liquid handling equipment, have announced the companies have entered into a collaboration to improve the production and handling of 3D microtissues (spheroids).

“InSphero develops microtissues using the most advanced 3D cell culture technologies to produce highly predictive, organotypic in vitro models that are ready to use in critical applications including drug discovery, efficacy and safety,” said Wolfgang Moritz, PhD, InSphero co-founder. “Through this collaboration, we will leverage Hamilton’s breakthrough MagPip™ liquid and cell handling technology to optimize the processes used to produce and manipulate these microtissues.”

With the ability to rapidly and accurately transfer liquid volumes in a sub-microliter range, the MagPip™ liquid handling system allows for precise and gentle handling of even the most delicate microtissues without harming their integrity.

“The combination of InSphero’s advanced 3D in vitro models and our MagPip™ technology on the Microlab VANTAGE ™ will allow us to explore new ways to not only produce microtissues, but potentially expand how they are used in a wide range of applications,“ said Patrick Pfenninger, Senior Product Manager, Hamilton. “We expect MagPip enable new opportunities in microtissue sorting and storage, as well as in the areas of downstream processing for drug efficacy and safety testing.”

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3D InSight™ Human Liver Microtissues

InSphero

Discover the 3D InSight™ Human Liver Microtissues: the gold standard for Hepatotoxic screening. Pharma-validated co-culture models offer 2x higher DILI prediction sensitivity than 2D hepatocytes. Features pooled PHH from male/female donors co-cultured with Kupffer cells and LECs, 28-day viability, in 96-well format. Includes 50mL 3D InSight™ Liver Maintenance Medium. Check the bi-weekly production schedule online. 

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Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.In VitroIn vitro refers to experiments conducted outside living organisms, often in controlled lab environments such as petri dishes or test tubes. In vitro models are widely used in drug testing, cell biology, and disease research. Explore in vitro research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.MicrotissueLiquid HandlingLiquid handling involves the precise transfer, mixing, and dispensing of liquids in laboratory settings. It is essential for accurate and consistent results in biological, chemical, and pharmaceutical research. Automated liquid handling systems improve efficiency and reduce human error in sample preparation and analysis. Explore liquid handling tools in our peer-reviewed product directory; compare products, read customer reviews, and get pricing directly from manufacturers.
InSphero and Hamilton have announced collaboration to improve the production and handling of spheroids using advanced liquid handling technology