Infinite® 200 PRO Offers Environmental Control for Cell-based Applications

9 Dec 2010
Kerry Parker
CEO

Product news

Tecan has launched a Gas Control Module (GCM™) for its Infinite 200 PRO multimode microplate reader, creating one of the most comprehensive solutions on the market for cell-based assays.

Variations in environmental conditions can lead to inconsistent and unreliable data for cell-based optical studies, due changes in the pH and color of the media during incubation. By offering precise regulation of oxygen or carbon dioxide levels within the reader chamber, the GCM provides a more stable culture environment over time. This makes it ideally suited to in vitro investigation of eukaryotic cell lines, achieving better cell viability and allowing the duration of cell-based experiments to be extended without adversely affecting results.

The GCM also ensures greater biological relevance for a wide range of studies, by allowing assays to be performed under hypoxic or physiological conditions. This will extend the experimental window of microplate-based investigations using anaerobic or facultative anaerobic bacteria, allowing incubation within the reader chamber. It also allows the Infinite 200 PRO to be used for a range of biomedical studies, providing researchers with a simple mechanism for studying cell behavior under changing environmental conditions, mimicking events such as ischemia or oxidative shock for in vitro investigation.

To find out more on Tecan’s Infinite 200 PRO, visit the company website.

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Infinite® 200 PRO Offers Environmental Control for Cell-based Applications