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In the News this Week: Caffeine and Sports Performance, New Diabetes Assay & Controlling Gene Expression

SelectScience
3 Jul 2014
Sarah Thomas
Associate Editor

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Read our top stories in the news this week:

Caffeine Effects on Sporting Performance – Part 1: Metabolism Studies
With the World Cup in Brazil capturing the eyes of the world and the start of the Tour de France this week (unusually, this year’s famous French cycle race begins in Yorkshire, England), SelectScience is looking at the slightly controversial performance-enhancing effects of caffeine.

Adiponectin – New Diabetes Assay Identifies At Risk Patients
The extensive diabetes assay range available from Randox Laboratories has been further expanded with the recent addition of the new CE marked adiponectin assay.

RNA-Seq Webinar Describes Novel Insights into the Control of Gene Expression
Oxford Gene Technology (OGT), The Molecular Genetics Company, has made the latest in its series of educational webinars available to watch online. In the webinar entitled “Developing new insights into gene expression using RNA-Seq”, Dr Christopher Jones, Research Fellow at the Brighton and Sussex Medical School (BSMS), UK, presents novel findings from a recent RNA-Seq project performed by OGT.

New High Content Screening Platform for Quantitative Cell-Based Imaging
Cell biologists have a new imaging and analysis software available to them that offers speed, flexibility and efficiency for large-scale, high-throughput biology, including complex morphological analyses of cells, cell structure, and aggregations of cells in colonies. While robust, the platform is also simple enough to be applied to everyday assays such as viability and proliferation.

Drug Discovery & Development Community News Round-Up
Read about the latest news in the Drug Discovery & Development community this month, including a new method for histone modifier screening, an article about ‘onion’ vesicles, and an innovative new method of drug delivery.

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Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. DiabetesDiabetes is a metabolic disorder characterized by high blood sugar levels, either due to insufficient insulin production or resistance to its effects. Ongoing diabetes innovation focuses on developing better diagnostic tools, treatments, and preventive measures. Browse our peer-reviewed product directory to find the best diabetes diagnostic tools, compare products, check reviews, and get pricing directly from manufacturers.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.World CupRNA-SeqRNA sequencing (RNA-seq) is a next-generation sequencing technique used to analyze the transcriptome, providing insights into gene expression and regulation. This method is essential for genomics, disease research, and personalized medicine. Explore RNA-seq tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Caffeine

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