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In the News this Week: Advancing Alzheimer’s Research, Novel Methods for Biofuel Production, Breast Cancer Risk Study, and More…

SelectScience
21 Feb 2014
Sarah Thomas
Associate Editor

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Read this week’s top five stories about the latest scientific innovations:

Identifying the Best Microbes for Biofuel Production with AFM-IR
Anasys Instruments reports on the publication in the Journal of Physical Chemistry Letters demonstrating the use of AFM-IR used by French researchers to identify best microbes for biofuel production. The researchers conclude that their technique could greatly speed up the identification of microbes that could produce large amounts of bio-oil.

Precision-Guided Forensic Analysis of Highly Compromised Human Samples
Forensic scientists can now more quickly assess the quantity and quality of human DNA in highly compromised and degraded casework samples and provide the critical information needed to drive informed decisions on subsequent steps in the analysis process, thanks to two new DNA quantification solutions.

MammaPrint Test Validated for Long-Term Prediction of Breast Cancer Outcome
A newly published study concludes that the Agendia MammaPrint® breast cancer test can accurately stratify a woman's breast cancer risk for up to 25 years after she is first diagnosed with the disease.

New Quantitative ELISA for Alzheimer’s Disease Research
Enzo now offers a high sensitivity APP ΔC31 ELISA Kit; a one-of-a-kind quantitative ELISA for Alzheimer’s research. The ELISA kit enables sensitive identification and quantification of APP ΔC31, a novel APP cleavage fragment associated with Alzheimer’s disease, detecting as little as 0.92 pM of APP ΔC31 in human cell lysate and cerebral spinal fluid samples.

New Preclinical Imaging Center of Excellence for the Americas
Bruker recently announced the official opening of a new Preclinical Imaging Center of Excellence for the Americas in Billerica, Massachusetts. The facility offers advanced development, demonstration and support facilities for Bruker’s industry-leading portfolio of preclinical imaging instrumentation and multimodal platforms.

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NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Atomic Force Microscopy / Scanning Tunneling MicroscopyAtomic force microscopes (AFM) and scanning tunneling microscopes (STM) are high-resolution forms of scanning probe microscope (SPM) used to generate topological information of a sample down to the atomic scale. Instruments can generate an image of the surface topology, manipulate objects and reveal information on localized properties such as Young’s modulus, conductivity, and magnetism. High-quality STM and AFM probes optimized for your application are available, as well as other SPM-based instruments such as scanning ion conductance microscopes (SICM) & near-field scanning optical microscopes (NSOM). Find the best AFM and STM equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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