Improving the Consistency and Efficiency of Early Drug Discovery with VIAFLO II from INTEGRA

15 Oct 2014

Product news

A leading UK supplier of early-stage drug discovery and development process services has improved the consistency and efficiency of its assays using VIAFLO II pipettes and a VIAFLO ASSIST from INTEGRA. By mounting a VIAFLO II electronic pipette on the VIAFLO ASSIST, the pipette’s protocols can be carried out fully automatically.

A senior scientist at the UK organization commented, “Our lab is extremely satisfied with the decision we made to purchase and incorporate INTEGRA’s VIAFLO II multichannel pipettes and the VIAFLO ASSIST pipetting assistant into our daily work. We use the VIAFLO ASSIST for automated multichannel pipetting applications including serial dilutions for a variety of assays such as ELISA’s and proliferation assays. For assays in which repeat dispensing is needed, the ASSIST is also used for preparation of assay plates”. She added, “Our lab also has a robotic system, but for a lower number of plates the VIAFLO ASSIST is preferred because its set up is very quick”. The spokesperson concluded, “Overall the consistency of assays has been improved due to the use of the new VIAFLO II pipettes and the automated pipetting capabilities of the VIAFLO ASSIST. Because VIAFLO ASSIST is easy to use, more people within our lab are integrating it into their daily work routines. The VIAFLO ASSIST has also helped us to improve efficiency, for example when we perform sandwich ELISAs. While one plate is being coated with antibody or buffer, another plate can be washed on a plate washer, so that these different tasks can be done in parallel”.

Multichannel pipettes are a valuable tool for laboratories working with microplates. However, prolonged and repetitive pipetting sessions pose the risk of strain and fatigue, which can result in repetitive strain injuries (RSI) and less reproducible results. The VIAFLO ASSIST together with INTEGRA’s VIAFLO II electronic pipettes form the perfect partnership to prevent users from RSI and to significantly increase the reproducibility of prolonged pipetting protocols such as serial dilutions, plate filling and reagent addition. By mounting a VIAFLO II electronic pipette on the VIAFLO ASSIST, the pipette’s protocols can be carried out fully automatically.

VIAFLO Electronic Pipettes

INTEGRA Biosciences

Electronic pipettes with touch wheel user interface.   VIAFLO pipettes accommodate any pipetting task at hand: from single transfers to complex protocols. An intuitive touch wheel interface and color display allows for the quickest volume changes and user friendly menu navigation. The ergonomic design enables effortless pipetting. The unique tip fitting of the VIAFLO pipette assures that GripTip pipette tips will never loosen, leak or fall off. VIAFLO Electronic Pipettes Features:   GripTip Pipette Tips - By designing our GripTips™ in tandem with VIAFLO pipettes, we have created a unique, integrated system that offers the securest pipette and pipette tip connection. High lateral resistance. This prevents tips from falling off when touching off a multichannel pipette within a 96 or 384 well plate. Low required tip attachment forces. Low required tip ejection forces. All tips seal at the same height ensuring a perfect touch off and increased precision when dispensing. Intuitive User Interface - A full color screen and a proven touch wheel interface offer quick and comprehensible menu navigation. Simply by moving a finger over the touch wheel, menus and settings can be accessed. All menus are spelled out on the clear to read screen making memorizing of abbreviations unnecessary. Convenient Pipette and Program Management - VIAFLO pipettes can be connected to a computer via USB port. With the free to use pipette management software VIALINK, custom programs can be created on the computer and then be transferred onto VIAFLO pipettes. For laboratories with many users or power users with many pipetting protocols, all custom programs can be stored and backed up in a library on the computer. Applications: Repeat Dispense Manual Pipetting Sample Dilution Reverse Pipetting Variable Dispense

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Pipettes and DispensersPipettes and dispensers are essential lab equipment used to dispense measured volumes of liquid accurately. Explore a range of manual and electronic pipettes, including single and multichannel, serological and volumetric pipettes, as well as a range of pipette tips. Bottle-top dispensers are also available for simple and fast solvent dispensing. Find the best pipettes & dispensers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Electronic PipetteElectronic pipettes are precision instruments used to transfer measured volumes of liquid in laboratory settings. They offer high accuracy, ease of use, and ergonomic benefits compared to traditional pipettes, reducing the risk of repetitive strain injuries. Electronic pipettes are widely used in molecular biology, chemistry, and diagnostics. Browse our peer-reviewed product directory to find the best electronic pipettes; compare products, check reviews, and get pricing directly from manufacturers.Serial Dilution