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Improve Cell Culture and Cell Line Generation with HAMILTON’s New Automation Solutions at BIOTECHNICA 2010

Hamilton
28 Sept 2010
Sarah Sarah
Marketing / Sales

Product news

Visit HAMILTON to discover more about the 3D CellHOST system, new ClonaCell® EasyPick and a dedicated Genomics Workstation that automates all processes of DNA/RNA handling and a drug discovery workstation for high throughput compound handling.

Traditional automated solutions imitate the manual handling of cells. These systems are usually very big, expensive and quite slow. One reason for this is that there are lots of transport steps to bring the cell culture flasks with cells to the liquid handling platform and back to the incubator. The GEM microcarrier technology allows an optimized cell culture process when automated on the 3D CellHOST system: The incubator, i.e. the BioLevitator, is integrated on the workspace of the 3D-CellHOST™. The cells do not have any longer to be transported; they are easily accessible for media changes and other processes.

The new ClonaCell® EasyPick unites STEMCELL Technologies ClonaCell media with Hamilton's advanced high-performing liquid handling robotics to meet the three most important aspects in developing cell lines - quality, speed and throughput.

Features of the ClonaCell® EasyPick:

• Quality liquid handling robotics
• Simultaneous selection and cloning of cells in ClonaCell Media
• Automated Colony Isolation
• Eliminates serial dilutions
• Reduces clone development time by up to 26 days
• Increases probability of isolating rare high-yielding clones
• Reduces downstream screening
• Limits contamination risk
• Integrated customized software

Both systems can be discovered at the HAMILTON booth G24 in Hall 9 - together with a dedicated Genomics Workstation that automates all processes of DNA/RNA handling and a Drug Discovery Workstation for High Throughput Compound handling.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Robotic WorkstationsRobotic workstations are automated platforms enabling the user to perform high-throughput, multi-application processes, from sample preparation tasks such as PCR set-up, DNA purification and NGS library preparation, to integrated sample prep and analysis workstations. Automation makes processes consistent, fast, precise and fully walk-away. Find the best robotic workstations in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Improve Cell Culture and Cell Line Generation with HAMILTON’s New Automation Solutions at BIOTECHNICA 2010