Illumina Announces Partnerships to Automate TruSeq® and Nextera® Sample Preparation Kits

20 May 2013

Product news

Illumina, Inc. today announced it is collaborating with leading providers of liquid handling robotic platforms to develop automation methods for its best-in-class TruSeq and Nextera Sample Preparation kits. Initial partners in this effort are Beckman Coulter Life Sciences, Eppendorf, Hamilton Robotics, PerkinElmer, and Tecan.

These partnerships, and the resulting methods, reflect Illumina's commitment to creating the simplest, most efficient next-generation sequencing (NGS) workflows, and represent an important step towards enabling complete, end-to-end solutions for customers.

"We are excited to work with the top automation providers to deliver solutions that can be readily implemented in the lab, thus saving time for our customers and making automation much more accessible," said Christian Henry, Senior Vice President and General Manager of Illumina's Genomic Solutions business. "TruSeq and Nextera sample preparation kits are designed with master-mixed reagents and simplified protocols to facilitate automation. In the long term, the new methods will allow more samples to be run simultaneously and with fewer errors, while freeing up resources so that customers can focus on their scientific goals."

Under the agreements, sample preparation kits sold by Illumina will be automated by the partners, who will develop, distribute and install the methods on customers' robots, as well as provide technical support. Illumina will assist during development, testing and promotion of the methods. Methods for TruSeq RNA Sample Preparation kits will be available by end of Q2 2013, with automation methods for additional TruSeq and Nextera kits to follow.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.NGS AutomationNGS automation streamlines next-generation sequencing workflows, increasing throughput, accuracy, and reproducibility. Automated solutions enhance productivity in genomic research, clinical diagnostics, and personalized medicine. Browse peer-reviewed tools to compare products, read reviews, and get pricing.Library GenerationLibrary generation refers to the construction of NGS libraries from RNA and DNA sources.Library PreparationLibrary preparation is a critical step in sequencing workflows, where DNA or RNA samples are converted into libraries for high-throughput, next generation sequencing. This step ensures accurate results and minimizes biases. Explore library preparation kits in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.