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ICx Nomadics to Feature Label-Free Interaction Analysis System at SBS 2010

ICx Nomadics, Inc.
5 Apr 2010
Sarah Sarah
Marketing / Sales

Product news

This year ICX Nomadics will feature the Label-Free Biomolecular Interaction Analysis system SensiQ Pioneer in an Exhibitor Tutorial on Thursday, April 15th in Room 126AB. John Quinn, Chief Scientist, will present the advantages of the Fast-Step™ Injection method for throughput improvements for kinetics analysis.

The SensiQ Pioneer continues the tradition of cost-effective biomolecular interaction analysis systems from ICx Technologies. The Pioneer is a three channel system designed to provide high sensitivity for studies such as small molecule-protein interactions and also high accuracy and precision for demanding kinetic and affinity determinations.

Application areas particularly suited to the Pioneer include:

- Antibody Screening and Characterization
- Protein-Small Molecule Interactions for Drug Discovery
- Protein-Protein Interaction Kinetics
- Antibody Quality Control
- Disease Mechanism Studies
- Biomarker Development

Incorporated into the SensiQ Pioneer are capabilities normally found in higher end systems. These capabilities include sample handling from microplates, vials, or tubes, in-line buffer degassing, gradient injection, detection to 150 Da, and 21 CFR Part 11 compliance. Advanced instrument control and data analysis software provide a powerful yet easy to use interface for producing high quality data. A wide range of surface chemistries are also available.

For more information about the affordable SensiQ Pioneer system visit booth 250.

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ICx Nomadics, Inc.Company website

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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