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Hudson Control Group Delivers ProLink™ Proteomics Workcell To Major Pharmaceutical Customer

Hudson Lab Automation
27 Sept 2006

Product news

Boehringer Ingelheim Pharmaceutical's research group, located in Ridgefield, CT., has accepted delivery of Hudson Control Group's ProLink™ Proteomics Workcell.

The ProLink is a fully-automated protein expression and measurement system that completely automates the multiple tasks essential to BI's protein expression studies, including:

  • PCR reaction cleanup
  • Transformation, plating and outgrowth
  • Colony picking, inoculation and outgrowth
  • DNA minipreps
  • DNA quantification and normalization
  • Protein purification

The ProLink is unique in its scope, encompassing the entire protein expression process in one, fully-automated, integrated workcell. It includes a robotic colony-picker, automated incubator, robotic pipettors, reagent dispensers, plate sealers, thermal cycler, and plate reader, serviced by Hudson's PlateCrane and LabLinx microplate-handling robots.

The system is powered by Hudson Control Group's opportunistic SoftLinx™ scheduling software, which finds the quickest, most efficient ways for processes to be performed simultaneously. A user can run multiple batches in different stages of the process at the same time, or run any instrument individually even while operating another, fully automated run.

The SoftLinx™ software also optimizes equipment usage by enabling it to be used for different processes simultaneously. In addition, it enables easy integration of all the equipment within the ProLink Express™ workcell, including instruments from other manufacturers.

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Integration ServicesIncorporate lab systems, software and equipment with integration services.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Hudson Control Group Delivers ProLink™ Proteomics Workcell To Major Pharmaceutical Customer