Hospital Expands Roche Modular SWA Platform to Offer a 24/7 Serology Service

9 Feb 2011
Sarah Sarah
Marketing / Sales

Product news

The Blood Science laboratory at the University Hospital Birmingham NHS Foundation Trust has introduced 13 serology assays onto their Roche Modular SWA platform, allowing them to offer a 24/7 serology service. As a leading organ and bone marrow transplant centre, this enables the laboratory to perform critical emergency transplant serology tests without the need for staff call-out.

The main Blood Science laboratory for the Trust is located at Selly Oak Hospital, with the Microbiology department and a satellite biochemistry laboratory on a different site at the Queen Elizabeth Hospital. In the past, serology assays were performed in the Microbiology Department on a stand alone instrument. Test were batched and performed during the working hours of the microbiology laboratory (Monday to Friday between the hours of 9 am and 5 pm and Saturday mornings). Emergency transplant serology tests were provided on an on-call basis.

Recently, in preparation for the opening of the Trust’s new Queen Elizabeth Hospital, the working processes for Pathology were reviewed. “For pathology we have based our design for the laboratories on processes rather than on the usual single disciplines,” explained Blood Science Laboratory Manager, Chris Gaskin. “As a result, for the first time, all pathology disciplines will be together on the same site. Chemistry, immunoassay, serology, transfusion, blood counts/films and coagulation testing will be combined in an automated Blood Science Laboratory.”

“We have already successfully consolidated haematinics and serology onto our existing Roche Modular platform in our main Biochemistry laboratory at Selly Oak,” Chris continued. “This has been extremely cost effective for us and has allowed us to increase our workload. The disciplines work very closely together, with Biochemistry responsible for the technical validation, and Haematology or Microbiology responsible for the clinical validation for haematinics or serology respectively.”

“Bringing automated serology testing into Biochemistry has freed up Microbiology staff for other tasks and, since the main Biochemistry laboratory operates 24/7, there is no longer the need for transplant serology call-outs, added Chris. “In addition, there are back up analysers in the Biochemistry lab, for added security, and the Modular Pre-analytics module minimises sample handling and reduces the potential for human errors. Our turnaround times for serology assays have improved and connectivity, which is enabled through our Roche PSM data management system, allows permitted microbiology staff and consultants to view results immediately.”

“Staff training is an ongoing part of the change in work processes,” concluded Chris. “This is delivered by Roche Product Specialists, Microbiology Consultants, BMS staff and the transplant nurses on an ongoing basis. Staff collaboration has been an important element in paving the way for good working relationships as we move to our new location.”

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MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.
Hospital Expands Roche Modular SWA Platform to Offer a 24/7 Serology Service