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High Purity New England unveils new line of bioreactors from Univercells Technologies

Univercells

New line of bioreactors is designed to ensure seamless scalability from early process development to commercial manufacturing

12 Mar 2021
Diane Li
Assistant Editor

Industry news

High Purity New England (HPNE), a leading supplier of solutions for the biopharma industry, has officially introduced a new line of fixed-bed, single-use bioreactors from Univercells Technologies for the US Market. This new highly scalable line of bioreactors is designed to ensure seamless scalability from early process development to commercial manufacturing. The scale-X™ fixed-bed bioreactor range and the NevoLine™ Upstream platform are available immediately in the U.S. market through High Purity New England.

The product line features intensified bioreactors offering growth surface areas from 2.4m² up to 600m² providing a significant increase of the surface area/volume ratio compared to conventional technologies. The fixed-bed structure provides a high surface area available for cell culture and viral production for gene therapy and vaccine applications in a very low footprint. It delivers similar fluid conditions at all scales, thus ensuring predictable cell & product behavior.This high density single-use bioreactor was created with a novel structured design for reliable & scalable production throughout upstream bioprocessing.

Integrated within advanced, automated upstream solutions, these bioreactors deliver continuously concentrated harvest for simplified purification. Process control functionalities enable continuous protocol execution & standard parameter monitoring. Additionally, the scalable design allows for the constant linear velocity of fluids and even distribution through the fixed-bed to ensure a smooth scale-up.

Based in Nivelles, Belgium, Univercells Technologies was launched in 2020 to focus on accelerating the commercialization of Univercells’ manufacturing technologies – including the scale-X bioreactor and the NevoLine platform. Univercells was founded in 2013 by José Castillo, a notable designer of previous single-use bioreactor systems that have transformed the vaccines and gene therapy industry and Hugues Bultot, experienced CEO and leader in cell culture process optimization.

As the U.S. supplier for Univercells Technologies, High Purity New England continues to supply the biopharma and biotech industries with a range of innovative products, from drug discovery and development to fill-finish, including their flagship product, custom single-use assemblies, as well as pumps, mixers, and other single-use solutions. Along with their own manufactured products for the global market, they are a distributor for 18 brands in North America. HPNE proudly supports numerous companies working on vaccines and therapeutics in the fight against COVID-19.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.BioreactorAutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.BioprocessingBioprocessing is the use of biological systems for the conversion of raw materials to desired products. This includes the research, development and manufacturing stages of production and can refer to food processing, small-molecule pharmaceutical manufacture, production of recombinant protein therapeutics, or the generation of renewable energy.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Vaccine DevelopmentVaccine development focuses on creating immunizations to protect against infectious diseases. The process involves identifying antigens, developing and testing vaccine efficacy, and ensuring safety through preclinical testing and multiple clinical trial phases. Scientists use various approaches, including weakened or inactivated viruses, protein subunits, or mRNA. Advanced platforms and rapid diagnostic tools aid in vaccine research and testing. Explore vaccine development solutions in our peer-reviewed product directory; compare products, read reviews, and get pricing directly from manufacturers. BiotechnologyBiotechnology is the use of biological processes, organisms, or systems in the production of products and services. It spans a wide range of applications, including healthcare, agriculture, and environmental management. Browse our peer-reviewed product directory to find the best biotechnology tools, compare products, check reviews, and get pricing directly from manufacturers.Gene TherapyGene therapy is a technique that modifies or replaces genes within an individual's cells to treat or prevent diseases. This approach holds potential for curing genetic disorders, cancers, and certain viral infections. Advances in gene editing technologies like CRISPR are driving the growth of gene therapy. Explore gene therapy tools and technologies in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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High Purity New England unveils new line of bioreactors from Univercells Technologies