NewsLife Sciences
Hidex microplate reader opens new applications in vascular and neurodegenerative disease studies
8 Feb 2007Product news
Evaluation of the Hidex Chameleon microplate reader revealed that the higher luminescence sensitivity of the reader is essential for the measurement of small changes in superoxidegeneration from living vascular cells under culture conditions.
Other fluorescent dyes sensitive to reactive oxygen species can be simultaneously detected by this microplate reader to confirm findings with lucigenin chemiluminescence.
The high sensitivity multi-technology capability of the Chameleon microplate reader makes it an ideal bench research apparatus for studies of oxidative stress in models of vascular, neurodegenerative and other diseases.
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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
