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Harnessing the immune system to fight cancer

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Join this expert webinar to find out about applications for cell-based therapies and biologics using advanced high-throughput flow cytometry

23 Apr 2020
Georgina Wynne Hughes
Editorial Assistant

Expert insights

Immunotherapies direct the body’s own immune system to identify and destroy cancer cells and are revolutionizing cancer treatment. In recent years, advancements in immuno-oncology have seen the development of antibodies targeting checkpoint pathways that can inhibit T cell exhaustion or reawaken exhausted T cells leading to more effective tumor killing, and even antibodies that can increase the engagement of immune and tumor cells stimulating killing by direct cytotoxicity or phagocytosis.

Cell engineering approaches to create T cells and NK cells that seek and destroy cancer present vast therapeutic potential, with T cell-based therapies already receiving regulatory approval. Therefore, a deeper understanding of immune/tumor cell interactions and processes leading to cancer cell eradication is critical to identify and validate new targets and therapeutic approaches.

In this upcoming SelectScience webinar, Dr. John O'Rourke, from Sartorius, will illustrate the use of advanced high-throughput flow cytometry to detect immune cell cytotoxicity with a variety of applications and model immunotherapeutics. Further focus is given to sample miniaturization and novel data visualizations to accelerate the time to actionable results.

REGISTER NOW

Attend the webinar to learn about:

  • Immune cell killing assays such as NK cell cytotoxicity
  • Implementing antibody-dependent cytotoxicity and antibody-dependent cellular phagocytosis assays
  • How high-throughput flow cytometry addresses bottlenecks in the development of biologics and cell-based therapies

The live webinar takes place on Thursday, May 7, 2020, at:

  • 16:00 BST
  • 11:00 EDT
  • 08:00 PST
  • 17:00 CEST

Who should attend:

Scientists and executives in biotechnology, pharmaceuticals and academia should attend.

Certificate of attendance

All webinar participants can request a certificate of attendance, and a learning outcomes summary document for continuing education purposes.

Scheduling conflict? No matter, register to receive an on-demand link to watch later>>

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cancer CellsCancer cells are abnormal cells that divide uncontrollably, leading to the formation of tumors and the spread of cancer. Studying cancer cells is crucial for developing new treatments and understanding tumor biology. Explore cancer cell research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.Flow CytometryImmunotherapyImmunotherapy is a treatment approach that utilizes the body�s immune system to fight diseases, especially cancer. It includes therapies such as monoclonal antibodies, checkpoint inhibitors, and CAR-T cell therapy. Immunotherapy is a rapidly growing area of research in oncology and autoimmune diseases. Browse our peer-reviewed product directory to find the best immunotherapy tools, compare products, check reviews, and get pricing directly from manufacturers.TherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.Engineered AntibodiesEngineered antibodies are modified to enhance specificity, stability, and functionality for therapeutic and diagnostic applications. These antibodies are central to immunotherapy and biomarker detection. Compare engineered antibody solutions in our directory to find top products and reviews.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.

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